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Acne overview

Acne is a common skin condition that results in red, bumpy, and blotchy skin, typically on the face. This generally occurs when hair follicles become clogged with oil or dead skin cells. This process leads to several types of skin problems, including pimples, whiteheads, and blackheads.

While it primarily affects adolescents, the truth is acne can affect people at any age. The symptoms vary quite significantly from person to person. However, they all involve painful or uncomfortable bumps, which can cause quite a bit of turmoil for those affected.

Effective treatment plans are available, but there is no known “cure,” which will stop these issues for good. The painful pimples and papules will slowly heal over time, but for many, the relief is short-lived, as new bumps seem to appear as soon as the older ones start to heal.

Those with mild acne typically experience both whiteheads and blackheads. The difference between them is merely whether or not the pores are open, with blackheads having open pores and whiteheads having them closed. These issues can lead to inflammation when bacteria builds up, causing what is known as inflammatory acne. When this inflammation persists and gets worse, it can even permanently scar the skin.

After puberty, people have a larger amount of the hormone androgen in their system, which increases the skin’s oil production. This oil, also known as sebum, is useful in protecting and moisturizing the skin. However, when pores become blocked with dead skin cells, the sebum builds up and leads to blackheads, whiteheads, and pimples.

While we know androgen production is an important factor, we still don’t fully understand precisely what causes acne. The most commonly referenced risk factors of acne are things such as diet and not washing properly. However, there is very little scientific evidence supporting either of these theories. Instead, researchers believe things such as stress, hormones from certain medications, and certain skincare products can cause more blocked pores.

Acne is a prevalent condition, with some estimates saying around 90% of people experience acne at one point in their lives. While for the vast majority of people this will occur during the teen years, around 40-55% of adults aged 20-40 are diagnosed with some type of acne.

As such a common condition, which can scar skin for life, it’s crucial to find new and effective treatments for acne. If you or a loved one is dealing with acne, be sure to consult a doctor before starting any new medications. Especially if your acne is severe, they will provide the most relevant and useful information.

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Table of Contents

CBD Research For Acne

potencial impact research overview

Acne - Cannabidiol as a Treatment for Acne?

  • O’Shaughnessy’s Online
  • 2010

related conditions:

Acne

This article discusses a presentation by Tamas Biro, indicating CBD may be used to treat various skin conditions. They believe the endocannabinoid receptors in sebaceous glands and hair follicles play an essential role. Biro and others believe that cannabidiol can be used effectively to treat a wide range of conditions that are currently treated with harsher and more dangerous chemicals.

Acne - Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

  • The Journal of Clinical Investigation
  • 2014

related conditions:

Acne

Research shows that utilizing CBD is highly effective at correcting the sebaceous glands which are responsible for producing the skin's oil. That aspect, in combination with CBD's anti-inflammatory effects, showed it to be effective at treating skin blemishes and abnormalities. Overall, researchers found that CBD is highly promising as a therapy for skin conditions.

Acne - Endocannabinoid signaling and epidermal differentiation

  • University of Teramo
  • 2011

related conditions:

Acne

Researchers explore the endocannabinoid system's response to treatment with CBD. They look particularly to its effect on the differentiation or regulation between skin cell growth and death. The disruption of this regulation is the cause of a plethora of skin conditions and diseases. Ultimately they found that treating the endocannabinoid system shows great promise for the treatment of these conditions.

Acne - Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling

  • University of Debrecen
  • 2008

related conditions:

Acne

Researchers took a look at how skin reacts when treated with cannabinoids. They found that skin cells treated with cannabinoids, such as CBD, showed an improved regulation of lipid production and cell death. This proved that the use of cannabinoids ought to be researched even more for the management of various skin conditions, particularly those related to the sebaceous gland.

Acne - The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities

  • University of Debrecen
  • 2009

related conditions:

Acne

In this study, researchers looked at the endocannabinoid system and its presence in human skin, particularly at hair follicles and sebaceous glands. They found that cannabinoids, such as CBD, can affect the needs of the skin. The use of cannabinoids to protect the skin's delicate balance is promising for the treatment of various skin conditions and diseases.

CBD Research That Might Be Useful for Symptoms of Acne

potencial impact research overview

Inflammation - Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice

  • Tongji University School of Medicine
  • 2013

related conditions:

Inflammation

A study of mice concluded CBD has significant anti-inflammatory effects. The researchers also saw evidence that the expression of the GPR55 receptor was improved after starting on CBD. Treatment with CBD was shown to significantly decrease the levels of several inflammation-related chemicals in test subjects.

Anxiety - Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

  • University of Melbourne, Australia
  • 2013

related conditions:

Anxiety

A comprehensive review of all the plant-based medicine which has had both preclinical and human clinical trials conducted about their anxiolytic-like effect. An analysis of over 1500 papers identified 21 plants which had been adequately tested, with one of the most successful of these plants found to be CBD enriched Cannabis species.

Pain Relief - Control of pain initiation by endogenous cannabinoids

  • University of Naples Federico II
  • 1998

related conditions:

Pain Relief

Researchers concluded CBD significantly reduces discomfort and pain, in part, due to the interaction between two substances, PEA and anandamide. According to tests, they “act synergistically, reducing pain responses 100-fold more potently than each compound alone”.

Acne & CBD Research Overview

It hasn't taken very long for CBD to grow from an alternative medication, only known by the most devout homeopaths, to a worldwide phenomenon. Once you start to look into the evidence we have supporting CBD; it starts to become very clear why. In fact, research has pointed to several key ways in which CBD could benefit those suffering from acne.

A review of the available information called Cannabidiol as a Treatment for Acne? found strong evidence that the endocannabinoid receptors have a significant impact on any acne symptoms experienced. The evidence suggests CBD could actually be beneficial for a wide range of different skin conditions, not just acne.

Research has shown that a disruption in the normal functioning of the endocannabinoid system can lead to a whole host of issues, including skin conditions. Luckily reports such as Endocannabinoid signaling and epidermal differentiation have found CBD improves the balance between skin cell growth and death. The team concluded cannabinoids should be researched much further to understand their positive impact fully.

Researchers are currently working to understand precisely how and why CBD seems to play such an essential role in overall skin health. The team behind The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities found strong evidence cannabinoids, such as CBD, are extremely useful in protecting the delicate balance of skin primarily thanks to the endocannabinoid system. Active receptors can be found in everything from hair follicles to the sebaceous glands themselves.

Another significant way in which CBD has been shown to improve acne is by reducing the inflammation, which usually goes along with moderate to severe acne. A report called, Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes, showed CBD treatment could effectively correct regulatory dysfunction in the sebaceous glands. The team concluded that this effect, in addition to the well documented anti-inflammatory benefits of CBD, indicates very promising applications for acne.

Other reports, such as Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling, have provided robust evidence that CBD is extremely effective at regulating the body's response. The team showed CBD significantly improved the regulation of lipid production and skin cell death. They believe more research is warranted to uncover the full impact of CBD, and how it's anti-inflammatory benefits might play a role.

This anti-inflammatory effect of CBD has been well researched and documented. For instance, Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice showed substantial evidence that CBD significantly reduces inflammation throughout the body. The researchers believe it works by regulating the types and levels of chemicals present in your system, altering your body's response.

Other well-documented benefits of CBD for those dealing with acne include reducing pain and anxiety. Reports such as Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence, and Control of pain initiation by endogenous cannabinoids, found robust evidence of these benefits. The research is clear. For those dealing with acne, CBD may be a viable treatment option for regulating your system.

Best CBD for Acne

NoteCBD Capsules (10mg)

NoteCBD Capsules (10mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$45.00
  • CBD Per Serving: 10mg
  • Number Of Servings: 30
  • Cost Per Serving: $1.50
  • Cost Per/mg of CBD: $0.15
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advantages

  • Full Spectrum
  • Lab Certified
  • Organic
  Servings per day Days supplied in one package Cost per week
Low Dosage (30 mg/day) 3.00 10.0 $31.50
Mid Dosage (45 mg/day) 4.50 6.7 $47.25
High Dosage (60 mg/day) 6.00 5.0 $63.00

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Pure CBD Oil Capsules, (50mg)

Pure CBD Oil Capsules, (50mg)

description

Every Day Optimal Soft Gel PCR Hemp Oil Capsule contains 50mg of pure CBD.

$119.99
  • CBD Per Serving: 50mg
  • Number Of Servings: 30
  • Cost Per Serving: $4.00
  • Cost Per/mg of CBD: $0.08
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advantages

  • Easy Capsule Form
  • All Natural
  • GMP Compliant
  Servings per day Days supplied in one package Cost per week
Low Dosage (30 mg/day) 0.60 50.0 $16.80
Mid Dosage (45 mg/day) 0.90 33.3 $25.20
High Dosage (60 mg/day) 1.20 25.0 $33.60

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NoteCBD Capsules (25mg)

NoteCBD Capsules (25mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$95.00
  • CBD Per Serving: 25mg
  • Number Of Servings: 30
  • Cost Per Serving: $3.17
  • Cost Per/mg of CBD: $0.13
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advantages

  • Full Spectrum
  • Gluten Free
  • Lab Certified
  Servings per day Days supplied in one package Cost per week
Low Dosage (30 mg/day) 1.20 25.0 $26.60
Mid Dosage (45 mg/day) 1.80 16.7 $39.90
High Dosage (60 mg/day) 2.40 12.5 $53.20

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Suggested CBD Dosage for Acne

Dosage Per Day

Low

30 mg

Mid

45 mg

High

60 mg

The most common question asked by users is precisely how much CBD should be taken for a given condition. Unfortunately, the human body is extremely complex, and as such, everyone’s ideal medication may be slightly different. As such, we suggest each person try a bit of experimentation in order to determine what a perfect dosage is.

That said, we can still offer a reliable starting place to begin your experimentation. According to experts at TheExtract.com, around 20mg of CBD twice a day is enough to decrease sebum production.

It’s also essential to remember that while CBD has become commonplace in many areas, it’s still not totally legal everywhere. In fact, some places even still treat CBD and THC as the same, despite all the clear and distinct differences. As such, you should always double-check any laws when purchasing CBD, and especially before traveling.

We should also mention that while a majority of CBD products tend to be THC-free, there are plenty out there which still contain a bit of the psychoactive cannabinoid. As such, you should ensure any product you buy is 100% THC-free if you’re unwilling or unable to get high.

Regardless of how you decide to take your CBD, we sincerely hope you choose to leave your experiences here for others to learn from. All it takes is a short overview of your time using CBD, along with a score for the major symptoms. Together we can build a much more well-informed and healthy world.

Tracking CBD Effectiveness For Acne

One thing that many people find difficult when first starting to take CBD is how to zero-in on precisely how well it’s working for you. This can be quite frustrating, as even when working properly, the effects of CBD are usually quite subtle. Luckily, when it comes to acne, the results should be a bit more clear.

That said, it’s still essential to try CBD for a few weeks, while keeping track of your results, to truly understand whether or not it worked for you. Everyone has a different system, and as such, may require a slightly different ideal regimen. Something we suggest to everyone starting CBD is to keep a small journal of doses and subsequent symptoms. This little tip can make a huge difference.

Some people may start to notice a difference in the health and clarity of their skin in just a few days, while for others, it might take a couple of weeks if it ends up working at all. Between CBD being a relatively new medication option, and the overall complexity of human systems, finding the perfect dosage for you is going to require some hands-on experimentation.

People often ask if they “have” to keep a journal for CBD to work effectively. While it’s not technically required, we do strongly suggest following this routine to maximize the effectiveness of your CBD, as well as more rapidly determine how effective it is for you.

If you do decide to keep track of your progress with CBD, we hope that you consider leaving your experience below to help others learn. All we need is a short description of your time using CBD, along with a score for how well you think it improved your acne, inflammation, and pain. The more accessible information we have for newcomers, the easier it will be for people to treat their ailments with CBD successfully.

Experiences Using CBD for Acne

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