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Arthritis overview

Arthritis affects over 350 million people worldwide, with around 40 million coming from the US alone. Arthritis is inflammation of one or more joints in your body which leads to pain and stiffness that typically gets worse as you age. While there are many different causes and types of arthritis, the symptoms and treatments tend to be the same. The two most common types of arthritis are osteoarthritis, which occurs over time as the cartilage between joints weakens, and rheumatoid arthritis, which is caused by an autoimmune disorder that targets the lining of joints. Regardless of the cause, the pain is a direct result of swelling, which tends to be worse in weight-bearing joints such as the knees or spine.

There is currently no known cure for arthritis, but successful treatment aims to reduce pain and increase the quality of life. It’s also one of the most significant problems facing public health in America, as reports show arthritis is the leading cause of disability among adults in the US. Making matters worse, around two-thirds of all adults suffering from arthritis are still within “working age” (18-64 years old). As you can imagine, there are plenty of people out there who are in desperate need of something to ease their arthritis-related pain.

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CBD Research For Arthritis

potencial impact research overview

Arthritis - Arthritis and cannabinoids: HU‐210 and Win‐55,212–2 prevent IL‐1 α‐induced matrix degradation in bovine articular chondrocytes in‐vitro

  • Royal Pharmaceutical Society of Great Britain
  • 2006

related conditions:

Arthritis

CBD was shown to have “analgesic, immunomodulatory and anti‐inflammatory properties.” Researchers determined a CBD regimen reduces joint damage from arthritis, mainly by strengthening cartilage. They also noted several different ways in which the body reacts favorably to the introduction of CBD, especially in mitigating the degradation and inflammation induced by cytokines.

Arthritis - Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis

  • Royal National Hospital for Rheumatic Diseases, Bath, UK
  • 2006

related conditions:

Arthritis

CBD was observed to provide a “significant analgesic effect” for those suffering from rheumatoid arthritis. This includes improvement in pain on movement, pain on rest, quality of sleep, and pain at present. In addition, disease activity was significantly suppressed after treatment. The vast majority of side effects were mild, with some considered moderate, but none serious.

Arthritis - The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55

  • Department of Physiology & Pharmacology, University of Calgary
  • 2011

related conditions:

Arthritis

Research proves CBD bonds to many more receptors in the brain than previously believed. Not only are atypical receptors involved, but researchers found clear evidence they’re involved in joint nociception. As such, they believe CBD could play a significant role in finding new and effective treatments for various types of inflammation-related pain.

Arthritis - The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

  • Kennedy Institute of Rheumatology, London,
  • 2000

related conditions:

Arthritis

CBD was shown to “effectively block progression of arthritis” in both classical acute and chronic relapsing cases. There were also clinical improvements in the protection of joints against severe damage. Encouragingly, the powerful effects of CBD were shown both in vitro and in vivo. This research provides solid support for the immunosuppressive and anti-inflammatory properties of CBD.

CBD Research That Might Be Useful for Symptoms of Arthritis

potencial impact research overview

Inflammation - Cannabidiol (CBD) and its analogs: A review of their effects on inflammation

  • Department of Biochemistry & Molecular Pharmacology, University of Massachusetts Medical School, United States
  • 2015

related conditions:

Inflammation

CBD is now seen as the primary reason behind many of the benefits of marijuana. The researchers reviewed available reports on CBD to track important trends and applications. Anti-inflammatory properties were reported across a myriad of different preclinical models. These included neutrophil chemotaxis, autoimmune encephalomyelitis, as well as more common conditions such as arthritis.

Sleep - Cannabis, Cannabinoids, and Sleep: a Review of the Literature

  • Palo Alto University, CA, USA
  • 2017

related conditions:

Sleep

This report concludes CBD holds promise for significantly increasing the quality of REM sleep. Researchers believe it could one day be a primary force behind improved overall sleep quality. CBD was even shown to reduce daytime sleepiness in many patients.

Inflammation - Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress

  • Department of Pharmacology and Toxicology, School of Medicine, and Center for Excellence in Cardiovascular-Renal Research, University of Mississippi Medical Center, Jackson, USA
  • 2011

related conditions:

Inflammation

According to the report, there is growing reason to believe CBD plays a positive role in treating several human diseases and disorders now known to involve activation of the immune system and associated oxidative stress. It could play a significant role in treating severe conditions such as types 1 and 2 diabetes, rheumatoid arthritis, Alzheimer disease, neuropathic pain, and even depression.

Arthritis & CBD Research Overview

We have a growing pile of evidence which supports the value of CBD as a treatment for various types of arthritis. In fact, a report called Cannabidiol (CBD) and its analogs: A review of their effects on inflammation makes the case that CBD is the primary factor behind many of the medicinal benefits of marijuana. As you could imagine, most of the outside research proves CBD is effective in reducing inflammation or reinforcing joint cartilage. For instance, a study conducted by researchers at the Kennedy Institute of Rheumatology called, The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis, shed some light on the value of CBD for reducing inflammation. They tested the effect of CBD on the onset of arthritis in lab mice. Interestingly, they determined both injections and oral doses of CBD are effective at reducing pain, albeit at different levels. The researchers even replicated their results with types of arthritis much more similar to forms of the condition found in humans.

A separate study reached similar conclusions when the researchers said, “This study clearly shows that atypical cannabinoid receptors are involved in joint nociception and these novel targets may be advantageous for the treatment of inflammatory pain.” This report, called The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55, looked to confirm if CBD improves pain from vital parts of your joints, such as nociceptors. After collecting and analyzing all their data, the team was thoroughly convinced of the value.

The reasons behind this value may be closer to being solved, as a report called Arthritis and cannabinoids: HU‐210 and Win‐55,212–2 prevent IL‐1 α‐induced matrix degradation in bovine articular chondrocytes in‐vitro shed some light. The researchers concluded CBD is particularly effective at protecting cartilage from degradation thanks to a previously unknown CB-receptor. Even better, another report called Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis provides substantial evidence daily CBD treatments are effective at improving arthritis symptoms in humans. After analyzing all their data, the team reported not only was pain reduced in a statistically significant manner, but the vast majority of participants reported no adverse side effects whatsoever. A report called Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress indicated CBD is an effective treatment for arthritis as well as several other debilitating conditions related to activation of the immune system.

But what about all the issues that come along with arthritis, such as quality of sleep? This is one of the more common, and debilitating, issues commonly reported along with arthritis. As such, any relief from poor quality sleep is much needed. A report called Cannabis, Cannabinoids, and Sleep: a Review of the Literature makes a strong case that CBD is once again a fantastic choice. The team not only determined the quality of REM sleep is greatly increased, but starting a regimen of CBD was also shown to lower the likelihood of being excessively tired during the day.

Best CBD for Arthritis

Pure CBD Oil Capsules, (50mg)

Pure CBD Oil Capsules, (50mg)

description

Every Day Optimal Soft Gel PCR Hemp Oil Capsule contains 50mg of pure CBD.

$119.99
  • CBD Per Serving: 50mg
  • Number Of Servings: 30
  • Cost Per Serving: $4.00
  • Cost Per/mg of CBD: $0.08
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advantages

  • Easy Capsule Form
  • All Natural
  • GMP Compliant
  Servings per day Days supplied in one package Cost per week
Low Dosage (50 mg/day) 1.00 30.0 $28.00
Mid Dosage (75 mg/day) 1.50 20.0 $42.00
High Dosage (100 mg/day) 2.00 15.0 $56.00

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Relax Full Spectrum CBD Oil (3500mg)

Relax Full Spectrum CBD Oil (3500mg)

description

Relax Full Spectrum CBD Oil, available with an oil tincture dropper, delivers the ideal amount of CBD to meet all of your wellness needs. Made in the USA  from 100% high quality industrial hemp, this 3500 mg bottle of CBD is perfect for those wanting to combat stress, anxiety, and chronic pain.

$168.00
  • CBD Per Serving: 116.67mg
  • Number Of Servings: 30
  • Cost Per Serving: $5.60
  • Cost Per/mg of CBD: $0.05
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advantages

  • 100% Hemp Product
  • Made in USA
  • Full Spectrum
  Servings per day Days supplied in one package Cost per week
Low Dosage (50 mg/day) 0.43 70.0 $16.80
Mid Dosage (75 mg/day) 0.64 46.7 $25.20
High Dosage (100 mg/day) 0.86 35.0 $33.60

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Diamond CBD Full Spectrum Honey Tincture (2500mg)

Diamond CBD Full Spectrum Honey Tincture (2500mg)

description

These tasty new honey tinctures are made of 100% all-natural honey, presenting a delicious addition to how to deliver you with the ideal amount of CBD. Available in strengths ranging from 25mg to 3500mg, add it to your morning coffee, tea, or just use it throughout the day to sweeten up every moment while enjoying all of the awesome benefits that CBD offers.

$128.00
  • CBD Per Serving: 83.33mg
  • Number Of Servings: 30
  • Cost Per Serving: $4.27
  • Cost Per/mg of CBD: $0.05
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advantages

  • Honey Flavor
  • Control Over Dosing
  • All Natural Ingredients
  Servings per day Days supplied in one package Cost per week
Low Dosage (50 mg/day) 0.60 50.0 $17.92
Mid Dosage (75 mg/day) 0.90 33.3 $26.88
High Dosage (100 mg/day) 1.20 25.0 $35.84

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Suggested CBD Dosage for Arthritis

Dosage Per Day

Low

50 mg

Mid

75 mg

High

100 mg

One of the most common questions we get regarding CBD is how much you should take for various conditions. The truth is the perfect amount is different for everyone, so a bit of experimentation is likely required. However, there are a few simple tips you can follow when just starting out according to advice from arthritis.com. Low doses seem to be more effective for pain relief, as is slowing stepping up the dosage. Therefore it’s best to start with a small amount between 5mg and 10mg, twice daily, before eventually working your way up to between 50mg and 100 mg daily. They also suggest you only take CBD at night when you’re first starting out, and to avoid edibles unless you already know how it’s going to affect you personally. Lastly, they suggest trying a type of CBD with a small amount of THC still present if the CBD alone isn’t quite having the desired effect. But as always, take caution when using psychoactive substances such as THC.

Tracking CBD Effectiveness For Arthritis

It can be challenging to track your progress with CBD if you don’t know what you should be looking out for. Those who reported significant improvements in arthritis symptoms after starting CBD usually notice a reduction in joint pain and improved quality of sleep first.

Most research agrees one of the primary ways CBD relieves pain is through its anti-inflammatory properties. As such, any noted reduction in swelling and related pain is a sure sign that the CBD is working its magic. It’s also worth mentioning that CBD is entirely non-psychoactive, unlike THC, so most side-effects are mild and shouldn’t affect your day-to-day life.

So if you want to help others improve their quality of life, let us know about your experiences treating arthritis with CBD. Leave us your personal experiences along with a grade for the effectiveness of CBD in several categories, including joint pain, inflammation, and quality of sleep. Together we can help others understand what they could gain.

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