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Bladder Cancer overview

Bladder cancer is a common type of cancer that affects the cells lining the inside of your bladder. While it almost always occurs in the bladder itself, this type of cancer can actually occur anywhere in the urinary tract drainage system. According to studies, around 7 out of 10 cases of bladder cancer diagnosed are still in the early stages, making a full recovery much more feasible.

The significant signs of bladder cancer typically include painful, bloody urination, along with pelvic pain. Those who experience blood in their urine, otherwise known as hematuria, could have bright red colored pee, or it could be indetectable via the human eye. This can make getting an accurate diagnosis much harder.

Other common early complications of bladder cancer include back pain and having to pee all the time. It’s important to see a doctor as soon as possible. There are many other problems that could be the source of these symptoms.

There are several different types of bladder cancer. Which kind of cell developed into cancer determines the type. Urothelial carcinoma is the most common type of bladder cancer, affecting the lining. Squamous cell carcinoma, on the other hand, is related to chronic irritation of the bladder, and it’s more common in other parts of the world. Finally, Adenocarcinoma begins with the cells that constitute the mucus-secreting glands of the bladder.

The precise causes of bladder cancer are still being confirmed, but we have a solid grasp on how it begins to form. Cancer that develops in the bladder will cause cells to reproduce abnormally and at an increased pace. Things such as exposure to harmful chemicals and even parasitic infections can lead to the development of bladder cancer.

A major complication risk for all types of cancer is the risk of metastasizing or spreading to other parts of the body. Once this happens, experts agree this makes cancer much more difficult to treat in most cases. When it comes to bladder cancer, it generally spreads to organs such as the lungs, liver, or bones, but it can end up anywhere.

Many of the main risk factors for developing bladder cancer are things we have no control over, such as increasing age, sex, ethnicity, and family background. However, we can control other factors, including smoking, and exposure to harmful chemicals. Another significant risk factor is having had previous cancer treatments. Once you face a cancer diagnosis, even if it goes into remission, you’ll likely have a higher risk for the rest of your life.

Bladder cancer is a relatively common type of cancer, with nearly 75,000 people diagnosed each year. Men make up the vast majority of cases, with of the 75,000 cases, only around 18,000 being women. While figures have been improving over the years, nearly 20,000 people still lose their lives to bladder cancer every year.

Bladder cancer is a grave issue that must be handled properly. If you’re worried you or a loved one could be facing a cancer diagnosis, don’t wait to talk to a medical professional as soon as possible. Only they can offer you an accurate picture of the problem and get you on the best path.

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Table of Contents

CBD Research For Bladder Cancer

potencial impact research overview

Bladder Cancer - TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer

  • Nagoya City University
  • 2010

related conditions:

Cancer - Bladder

This experiment investigates the functional expression of the TRPV2 receptor in human cancers to determine if it may induce apoptotic cell death. Researchers found that the administration of CBD caused apoptotic cell death through TRPV2 expression, notably a continuous influx of calcium via that receptor. In conclusion, the authors note that TRPV2 channels may be a potential therapeutic target in the treatment of various cancers.

Bladder Cancer - Association Between Cannabis Use and the Risk of Bladder Cancer: Results From the California Men's Health Study

  • Kaiser Permanente Los Angeles Medical Center
  • 2015

related conditions:

Cancer - Bladder

Researchers sought to investigate the association of cannabis use on the incidence of bladder cancer, using the California Men's Health Study cohort. Evaluating the records of over 80,000 multiethnic participants ranging from ages 45-69, researchers found that cannabis use was associated with a 45% reduction in bladder cancer incidence. The authors determined that although cause and effect have not been established, cannabis use may be inversely associated with bladder cancer risk.

Bladder Cancer - Inhibitory Effect of Standardized Cannabis sativa Extract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility

  • University of Naples Federico II
  • 2011

related conditions:

Cancer - Bladder

In this study, researchers evaluated the effect of CBD on bladder contractility in vitro. Their results showed that CBD significantly reduced contractions, partially modulated by the TRPV1 receptor. The team noted these results provide a pharmacological basis to explain the efficacy of CBD in treating bladder contractility, associated with an elevated risk of cancer.

Bladder Cancer - Bladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism

  • Vita-Salute San Raffaele University
  • 2017

related conditions:

Cancer - Bladder

Using immunohistochemistry, researchers explored the inhibitory effects of cannabinoid receptor activation on cancer proliferation and migration, which may play a critical role in controlling certain types of cancer. Immunohistochemistry showed specific reactivity for both the CB1 and CB2 receptors, indicating these cannabinoid receptors control cell function in cancer cells. This data supports the use of CB2 as an active antitumor target and urges research into the development of other non-psychotropic CB2 agonists as a novel treatment.

CBD Research That Might Be Useful for Symptoms of Bladder Cancer

potencial impact research overview

Anxiety - Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

  • University of Melbourne, Australia
  • 2013

related conditions:

Anxiety

A comprehensive review of all the plant-based medicine which has had both preclinical and human clinical trials conducted about their anxiolytic-like effect. An analysis of over 1500 papers identified 21 plants which had been adequately tested, with one of the most successful of these plants found to be CBD enriched Cannabis species.

Inflammation - Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice

  • Tongji University School of Medicine
  • 2013

related conditions:

Inflammation

A study of mice concluded CBD has significant anti-inflammatory effects. The researchers also saw evidence that the expression of the GPR55 receptor was improved after starting on CBD. Treatment with CBD was shown to significantly decrease the levels of several inflammation-related chemicals in test subjects.

Nausea - Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews

  • Palo Alto University, CA, USA
  • 2017

related conditions:

Nausea

CBD was shown to significantly suppress vomiting in lab rats and shrews. Researchers used another substance, known as cannabigerol (CBG) to reverse this suppression. Moderate doses of CBG and CBD are opposing each other at the 5-HT1A receptor, which is known to play an essential role in regulating nausea.

Bladder Cancer & CBD Research Overview

It doesn't seem like all that long ago that few people understood the true benefits of CBD. For many years CBD was seen as little more than the little brother of THC, but the last couple decades of research have shifted this perspective wildly. These days we know of a wide range of conditions which CBD may potentially improve in one way or another, including bladder cancer.

Researchers have been able to determine that CBD treatment significantly reduces the proliferation via inducing apoptotic death in cancer cells. The team behind TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer showed CBD treatment causes this by expressing the TRPV2 receptors with an influx of calcium. As such, they identified the TRPV2 receptor as a potential avenue for treating various types of cancer.

Other reports have also provided evidence of the anticancer benefits offered by CBD. Bladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism concluded selective reactivity of the CB1 and CB2 receptors helps control cancer cell function. As such, they believe the activation of the CB2 receptor could represent a new treatment option in the fight against cancer spread.

Some researchers have even been able to show that taking CBD is associated with a much lower risk of developing bladder cancer in the first place. According to Association Between Cannabis Use and the Risk of Bladder Cancer: Results From the California Men's Health Study, CBD could even reduce your risk by nearly 50%. The team surveyed over 80,000 participants between 45-69 and found cannabinoid use correlated with a full 45% reduction in cases of bladder cancer.

Still, other researchers have found different ways in which CBD can reduce our overall cancer risk. Inhibitory Effect of Standardized Cannabis sativa Extract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility analyzed the ability of CBD to reduce bladder contractility, which is associated with a higher risk. The researchers showed that CBD could dramatically reduce bladder contractions, via modulation of the TRPV1 receptors.

There are several other, less direct, ways in which CBD can benefit those living with bladder cancer. Anxiety is consistently one of the most common complications of a cancer diagnosis. However, reports such as Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence have clearly proven CBD can help these people. The researchers analyzed over 1500 reports on plant-based anxiety meds before determining CBD to be the single most effective.

Many dealing with cancer will also face painful inflammation, depending on where the cancer is. That said, studies on this subject have been encouraging. Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice showed CBD could dramatically reduce the levels of inflammation-related substances in the system via the GPR55 receptor.

Finally, many people who are going through cancer treatments will experience moderate to severe nausea. As such, having access to effective medication is key. Reports, including Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews have shown CBD can do just this. In fact, CBD's interaction with the 5-HT1A receptors could reduce the strength and frequency of nausea symptoms.

Best CBD for Bladder Cancer

NoteCBD Capsules (25mg)

NoteCBD Capsules (25mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$95.00
  • CBD Per Serving: 25mg
  • Number Of Servings: 30
  • Cost Per Serving: $3.17
  • Cost Per/mg of CBD: $0.13
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advantages

  • Full Spectrum
  • Gluten Free
  • Lab Certified
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.80 37.5 $17.73
Mid Dosage (80 mg/day) 3.20 9.4 $70.93
High Dosage (175 mg/day) 7.00 4.3 $155.17

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Everyday Optimal CBD Oil Tincture (4000mg)

Everyday Optimal CBD Oil Tincture (4000mg)

description

CBD oil comes in many forms and potencies, but we haven’t seen any product sold by our competitors as powerful as our 4000mg cbd oil tincture. We make this powerful hemp oil product for people who demand fast, sure-fire relief from severe symptoms.

$289.99
  • CBD Per Serving: 133.33mg
  • Number Of Servings: 30
  • Cost Per Serving: $9.67
  • Cost Per/mg of CBD: $0.07
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advantages

  • Fast Effective Relief
  • Zero THC
  • Made In USA
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.15 200.0 $10.15
Mid Dosage (80 mg/day) 0.60 50.0 $40.60
High Dosage (175 mg/day) 1.31 22.9 $88.81

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NoteCBD Tincture (250mg)

NoteCBD Tincture (250mg)

description

Support your health and wellness with CBD-infused tinctures specifically formulated for human consumption. This tincture is made with full spectrum hemp oil, MCT oil, and essential oils.

$45.00
  • CBD Per Serving: 8.33mg
  • Number Of Servings: 30
  • Cost Per Serving: $1.50
  • Cost Per/mg of CBD: $0.18
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advantages

  • Full Spectrum Extract
  • Lab Certified
  • Made In USA
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 2.40 12.5 $25.21
Mid Dosage (80 mg/day) 9.60 3.1 $100.84
High Dosage (175 mg/day) 21.01 1.4 $220.59

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Suggested CBD Dosage for Bladder Cancer

Dosage Per Day

Low

20 mg

Mid

80 mg

High

175 mg

One question that we answer seemingly every day is precisely how much CBD is needed to treat the symptoms of a particular condition. It would be incredible if we just had a perfect answer for everyone that would work every time. Sadly, the world is more complicated than that, and finding your ideal routine will likely require some testing.

While we don’t have an exact number to offer, we do have the tools you need to figure it out for yourself. According to research, CBD has anti-proliferative effects on various types of cancer. Studies indicate that anywhere between 20-700mg per day could help mitigate tumor size. You should start on the low end of things and add or remove 10mg every few days, depending on what you’re experiencing.

While CBD has become a pervasive part of everyday life for many of us, it’s important to remember it’s not the case everywhere. In fact, some places even still treat CBD and THC as basically the same, making it illegal there. It would be best if you always double-checked before taking your CBD anywhere new.

We should also mention that while many CBD products will be CBD only, this isn’t always the case. Anyone unwilling or unable to get high should seriously consider making a habit of checking to ensure they only buy THC-free products. It’s worth noting that these products tend to keep THC in the mix to improve the desired effects, with research suggesting this includes the anti-tumoral effects.

Don’t be discouraged if you’re unsure of what to do when just starting out. There’s no shortage of conflicting information out there, and it can be hard to determine what’s worth listening too. That’s why we want to build a resource for all CBD users to utilize, as well as help build for newcomers. Whatever experiences you’ve had with CBD would be valuable insight for someone who doesn’t have any. We hope you choose to be part of this push.

Tracking CBD Effectiveness For Bladder Cancer

Many people who’re just starting a regimen of cannabidiol have trouble determining how well things are going. This can be very frustrating, but it’s important to remember that this is perfectly normal and happens to the majority of people. It’s also a great example of why often the best thing you can do is simply pay attention to what your body is telling you.

We believe a great way to combat this problem is by starting a simple journal of all your dosages and symptoms. While this can be tricky at first, after a few short weeks of keeping track, most people feel able to answer confidently if CBD works for them.

The thing that has the most direct impact on how CBD works for you will always be your personal system. What is the ideal routine for one person may not be nearly enough CBD for someone else. As such, the best way to know for sure if you’re getting the most out of your CBD is by doing the experimentation yourself.

One of the most popular questions we get is whether or not keeping a journal is something that must be done to increase the chances of success. While it’s entirely possible to get everything you want and need out of CBD without doing it, keeping a journal is one of the quickest and easiest ways to increase the effectiveness of whatever product you bought.

We really hope you choose to leave a brief overview of your experience here for others to learn from. Venturing out into the world of CBD can be quite mysterious, making user-generated information extremely valuable. We each hold a piece of the puzzle, and by sharing, we can make things much easier for any newcomers. All it takes is a short description of your time taking CBD along with a score for how well it improved any anxiety, inflammation, or nausea.

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