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Cancer overview

Cancer refers to any of a large number of diseases that are characterized by the growth of abnormal cells that divide uncontrollably. Cancerous tissue destroys healthy tissue as it spreads throughout the body. While cancer is the second-leading cause of death around the world, survival rates for many types are improving thanks to advances in treatment and screening.

The significant symptoms of cancer will depend on where it develops. Many people immediately think about the growth of hard lumps and tumors. However, there are more general symptoms that may occur in most types of cancer, including fatigue, unintended weight changes, changes in bowel/bladder function, and trouble swallowing. Others may experience persistent and unexplained fevers, indigestion, bruising, or muscle pain and weakness.

These symptoms can develop further alongside new complications. Pain, fatigue, and nausea are all common for those dealing with cancer and cancer treatments, but it can also be more complex. For instance, cancer can press on brain tissue and result in a wide variety of issues, including loss of function, strokes, and even personality changes.

Cancer that forms in one part of the body may spread to others, in a process called metastasizing. Where it spreads will be highly dependent on where it originated. Even when cancer goes into remission, there always remains a risk it will return. It’s incredibly crucial for cancer survivors to work with their doctor to devise a plan to mitigate risk and ensure regular screenings.

Cancer is caused by different mutations to the DNA within a given cell. The DNA found in each and every cell is split into a variety of genes, which each hold part of the information needed to reproduce cells. However, errors in this information can cause the cells to stop their normal function and even become cancerous.

These gene mutations can be something you’re born with or something that occurs during your life via smoking, radiation exposure, carcinogens, or other unhealthy choices. When they do occur, gene mutations generally affect cells in three distinct ways, allowing rapid proliferation, failure to stop excessive growth, as well as mutations that affect normal DNA repair processes.

Cancer is a widespread disease, with reports showing nearly 20 million new cases were identified in 2018 alone, along with 9.6 million deaths. A full 33% of these cases are linked to smoking, making it the leading cause of cancer. While survival rates have improved over the decades, estimates suggest there will be around 27.5 million new cases each year between now and 2040.

Given how serious of a diagnosis cancer is, the main priority for patients should be on prevention or a rapid treatment plan. If you’re worried you or a loved one could be facing a cancer diagnosis, don’t hesitate to visit your doctor and get tested. Only they can confirm and problems and get you on the right path forward.

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Table of Contents

CBD Research For Cancer

potencial impact research overview

Cancer - Cannabidiol as potential anticancer drug

  • University of Milan
  • 2013

related conditions:

Cancer

This review of the available information focuses on the efficacy of CBD in modulating various stages of cancer, as well as highlighting what cannabinoids may offer. The authors note that cannabinoid agonists are often looked over because of potential psychoactive effects and that CBD can provide therapeutic benefits without any psychoactive side effects. The review concludes that additional research is needed into CBD/CBD analogs to explore their full therapeutic potential.

Cancer - Cannabidiol inhibits angiogenesis by multiple mechanisms

  • University of Insubria
  • 2012

related conditions:

Cancer

This study evaluates the ability of CBD to modulate tumor angiogenesis, as well as exploring the anti-proliferative and pro-apoptotic actions of cannabinoids on various tumors. Using in vitro and in vivo models, researchers found that CBD induced HUVEC cytostasis without inducing apoptosis, caused by the down-modulation of several angiogenesis-related molecules. CBD inhibits angiogenesis by multiple mechanisms. Its dual effect on both tumor and endothelial cells shows CBD’s potential as a practical component in cancer therapy.

Cancer - The inhibitory effects of cannabidiol on systemic malignant tumors

  • Journal of Pain and Symptom Management
  • 2013

related conditions:

Cancer

This letter highlights a study investigating the long-term safety and tolerability of cannabinoid oromucosal sprays in patients with terminal cancer-related pain, resistant to opioid treatment. The study indicates CBD may attenuate tumor growth, as well as augmenting the effects of several malignancies. The author believes in the significant antineoplastic impact of CBD and calls for additional research to investigate those effects further.

Cancer - Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1

  • University of Rostock
  • 2010

related conditions:

Cancer

This study evaluates the impact of CBD on cancer cell invasion. Using Matrigel invasion assays, researchers found CBD impaired the invasion of several types of cancer in humans. The authors note the role CB1 and CB2 receptors may play in this mechanism, as well as TRPV1. The study concludes these findings demonstrate a novel mechanism, and that it may have therapeutic potential in treating invasive cancers.

Cancer - Marijuana Combats Cancer

  • Complutense University
  • 1998

related conditions:

Cancer

Researchers analyze the anti-cancer properties of cannabinoids, such as CBD, by researching cannabinoid-induced apoptosis. While screening brain cancer cells, researchers noticed that apoptosis would be induced under exposure to cannabinoids. The authors conclude that while more research is needed, CBD and related cannabinoids may confer a direct antitumor effect.

CBD Research That Might Be Useful for Symptoms of Cancer

potencial impact research overview

Anxiety - Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

  • University of Melbourne, Australia
  • 2013

related conditions:

Anxiety

A comprehensive review of all the plant-based medicine which has had both preclinical and human clinical trials conducted about their anxiolytic-like effect. An analysis of over 1500 papers identified 21 plants which had been adequately tested, with one of the most successful of these plants found to be CBD enriched Cannabis species.

Inflammation - Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice

  • Tongji University School of Medicine
  • 2013

related conditions:

Inflammation

A study of mice concluded CBD has significant anti-inflammatory effects. The researchers also saw evidence that the expression of the GPR55 receptor was improved after starting on CBD. Treatment with CBD was shown to significantly decrease the levels of several inflammation-related chemicals in test subjects.

Nausea - Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews

  • Palo Alto University, CA, USA
  • 2017

related conditions:

Nausea

CBD was shown to significantly suppress vomiting in lab rats and shrews. Researchers used another substance, known as cannabigerol (CBG) to reverse this suppression. Moderate doses of CBG and CBD are opposing each other at the 5-HT1A receptor, which is known to play an essential role in regulating nausea.

Cancer & CBD Research Overview

It hasn’t taken the CBD industry long to build a reputation as a powerful alternative medicine for many conditions. Over the last 15 years, in particular, researchers have discovered a ton of benefits to the highly tolerable cannabinoid, including in the treatment of cancer.

Studies such as Cannabidiol inhibits angiogenesis by multiple mechanisms have evaluated the antiproliferative and proapoptotic benefits of CBD. The team showed that CBD induced HUVEC cytostasis without increasing apoptosis in healthy cells. The dual impact of mitigating tumor progression and endothelial cells highlights the power of CBD as part of treatment plans for a wide range of cancers.

Another report, called Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1, analyzed the power of CBD to limit cancer cell invasion. The team noted the distinct role CB1, CB2, as well as TRPV1 receptors played controlling the proliferation of cancer. They concluded CBD demonstrates novel mechanisms that may help fight invasive forms of cancer.

This benefit has been shown by other researchers, including those behind Marijuana Combats Cancer. The purpose of the study was to analyze the anti-cancer properties of cannabinoids, including CBD. The researchers highlighted the ability of specific cannabinoids to induce apoptosis on cancer cells. While this result was clear, they believe more research is needed to say anything for sure.

More general looks at the impact of CBD on cancer have also yielded promising results. For instance, Cannabidiol as potential anticancer drug reviewed all the available research and highlighted the ability of CBD to provide benefits without any unwanted psychoactive effects.

Additionally, The inhibitory effects of cannabidiol on systemic malignant tumors, further notes the powerful benefits of CBD. Researchers showed that CBD could attenuate tumor growth while also altering the impact of different malignancies.

Apart from the specific benefits, CBD can provide in the fight against cancer; there are several symptoms that can be mitigated by treatment. Anxiety is a fairly common experience for those diagnosed with cancer. However, CBD is a powerful tool in the fight against anxiety, as reviews like Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence have shown. After reviewing over 1500 papers, the team concluded that CBD is the most potent plant-based drug we have.

Many with various forms of cancer will face increased inflammation. This can be a huge problem depending on where tumors are and where inflammation is worst. That said, CBD is a known treatment for painful inflammation. Reports such as Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice show interaction with the GPR55 receptor is vital in the regulation of inflammation.

Finally, some forms of cancer will result in frequent and painful headaches. CBD has been shown to help alleviate any nausea symptoms thanks to an interaction with the 5-HT1A receptor. A report called Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews concluded CBD treatment can significantly reduce the frequency and severity of nausea symptoms.

Best CBD for Cancer

Everyday Optimal CBD Capsules (200mg)

Everyday Optimal CBD Capsules (200mg)

description

Are you looking for something stronger than almost any CBD oil product on the market? Then you’ll love the newest addition to our high potency CBD line. With each capsule containing 200mg of pure CBD, you’ll experience all-natural, long-lasting relief for tough pain, sleep problems, anxiety, and more.

$299.99
  • CBD Per Serving: 200mg
  • Number Of Servings: 30
  • Cost Per Serving: $10.00
  • Cost Per/mg of CBD: $0.05
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advantages

  • Highest Capsule In USA
  • 100% USA Made
  • THC Free
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.10 300.0 $7.00
Mid Dosage (100 mg/day) 0.50 60.0 $35.00
High Dosage (300 mg/day) 1.50 20.0 $105.00

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Relax Full Spectrum CBD Oil (3500mg)

Relax Full Spectrum CBD Oil (3500mg)

description

Relax Full Spectrum CBD Oil, available with an oil tincture dropper, delivers the ideal amount of CBD to meet all of your wellness needs. Made in the USA  from 100% high quality industrial hemp, this 3500 mg bottle of CBD is perfect for those wanting to combat stress, anxiety, and chronic pain.

$168.00
  • CBD Per Serving: 116.67mg
  • Number Of Servings: 30
  • Cost Per Serving: $5.60
  • Cost Per/mg of CBD: $0.05
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advantages

  • 100% Hemp Product
  • Made in USA
  • Full Spectrum
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.17 175.0 $6.72
Mid Dosage (100 mg/day) 0.86 35.0 $33.60
High Dosage (300 mg/day) 2.57 11.7 $100.80

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Pure CBD Oil Capsules, (50mg)

Pure CBD Oil Capsules, (50mg)

description

Every Day Optimal Soft Gel PCR Hemp Oil Capsule contains 50mg of pure CBD.

$119.99
  • CBD Per Serving: 50mg
  • Number Of Servings: 30
  • Cost Per Serving: $4.00
  • Cost Per/mg of CBD: $0.08
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advantages

  • Easy Capsule Form
  • All Natural
  • GMP Compliant
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.40 75.0 $11.20
Mid Dosage (100 mg/day) 2.00 15.0 $56.00
High Dosage (300 mg/day) 6.00 5.0 $167.99

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Suggested CBD Dosage for Cancer

Dosage Per Day

Low

20 mg

Mid

100 mg

High

300 mg

If we had to guess, the most common question we get is how much CBD is needed to treat a given condition or symptom. We really do wish that we could just offer a simple answer that would work for everyone, but that’s just not the case. What it really takes is good old fashioned experimentation on your part.

But while we can’t offer the perfect dosage, we can offer a solid starting point for you to begin your journey with CBD. Different reports have shown that CBD may possess some powerful anti-tumoral effects for various forms of cancer. Over 700mg per day was shown to be well tolerated by humans, while between 20-40mg is a solid starting location. Researchers suggest adding or taking away 10mg every few days until you find your ideal routine.

Cannabidiol still isn’t legal all across the US. We’re getting closer to this being the case all the time, but for now, there are still many places that consider THC and CBD to be basically the same thing. That means if you get caught with CBD in these places, you could be subject to some serious legal trouble.

We should also take the time to mention that while most CBD products tend to be THC-free, this is far from the only case. There are plenty of CBD products that still contain a bit of THC to increase the effectiveness of treatments. This could even be the case when it comes to reducing cancer cells. That said, if you’re not able to be high, you must only opt for THC-free products from now on.

Many people can feel overwhelmed when sorting through all the data on CBD. But if you’re facing a cancer diagnosis, you likely already have plenty on your mind without having to stress about which sources are most trustworthy. We want to build a place for real CBD users to gather and share their experiences with each other. Please consider being a part of our movement!

Tracking CBD Effectiveness For Cancer

Something exhausting for those just beginning on CBD is understanding precisely how much it’s benefiting them. This can be a really frustrating downside for many, however, that doesn’t mean you’re alone. In fact, most people face this issue, given the subtle impact of CBD.

One thing that can help this issue a great deal is keeping a journal of your progress. With just a bit of tracking your daily doses and symptoms, you’ll feel much better equipped to answer the question of if CBD worked for you.

Everyone has a unique composition and may require a slightly different ideal regimen. What might work in a week for one person may take several for another, and not work much at all for a third. The best thing you can do to answer this question for you is simply listen to your body.

Most people wonder if keeping a journal is really something they need to do to be successful. While it’s entirely possible to be happy with your results from day one without a journal, nothing will as easily maximize your chances of understanding the impact of CBD.

If you do choose to track your progress with CBD, consider leaving a brief description of your experience here for others to learn from, along with a score for how well it improved any anxiety, pain, or nausea. With just a few minutes of your time, you can make a big difference in the life of someone who is just seeking answers. When it comes to cancer, the best thing we can do is offer each other as much information as possible. You never know what will make a difference in someone’s life.

Written By
John Mace Alois is lead content creator at the Did CBD Work? project. He’s analyzed over 400 research papers related to Cannabidiol and helped publish over 55 works related to different conditions for the project. He majored in Cultural Anthropology, with a minor in English, from the University at Albany. He is an avid collector of art supplies and refurbishes old furniture in his spare time.

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