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Colon Cancer overview

Colon cancer is a type of cancer that begins in the large intestine, the final portion of the digestive tract. It typically starts with small non-cancerous groups of cells called polyps forming in the colon. Over time, the polyps can develop into colon cancer cells.

As with most types of cancer, there aren’t many symptoms of early stages, especially before polyps develop into cancer. However, once they do, people often experience a constant change in bowel habits, rectal bleeding, and persistent abdominal pain. Others feel as if their bowels haven’t emptied completely, with an unexplained weakness or weight loss.

As with all types of cancer, one of the most significant complications is the metastasizing or spreading of cancer to other organs. Colon cancer most commonly spreads to the liver first but is also known to move to the lungs, bones, brain, and spinal cord. Once cancer spreads, it becomes a lot more challenging to deal with, making early detection and screening paramount.

Doctors still don’t know what causes most forms of colon cancer. Generally speaking, colon cancer begins when healthy colon cells start to develop mutations in their DNA. This DNA is split into different genes, each with their own portion of the data needed to make new cells. When this information becomes corrupted, cells cease normal function and may become cancerous. This often causes cells to grow at an alarming rate, damaging healthy cells as they proliferate.

While researchers don’t know precisely what causes colon cancer, they have identified several key risk factors. Some of these are things out of our control, such as age, race, and family history. African-Americans have a higher risk of colon cancer, as do people over the age of 50. However, other risk factors such as obesity, diet, and exercise can all impact your chances of developing colon cancer. For instance, low-fiber, high-fat diets have been linked to greater risk, along with a sedentary lifestyle.

Colon cancer is a widespread problem, with estimates saying over 100,000 people in the US will be diagnosed with colon cancer this year alone. That makes it the third most common type of cancer in both men and women, excluding skin cancer. While it’s most common in people over 50, rates in younger adults have been on the rise, but researchers don’t yet know why.

Colon cancer is a very serious diagnosis, so the primary focus should be on prevention and timely treatment. If you have any concerns you or a loved one could be dealing with colon cancer, be sure to talk to your doctor as soon as possible. Only a medical professional can provide a diagnosis and get you on the best path forward.

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Table of Contents

CBD Research For Colon Cancer

potencial impact research overview

Colon Cancer - Towards the use of non-psychoactive cannabinoids for prostate cancer

  • National Institutes of Health
  • 2013

related conditions:

Cancer

Researchers analyzed the palliative effects of cannabis and related cannabinoids in helping to provide relief to cancer patients. The authors note the potentially-adverse psychoactive effects of THC and the benefit that further research into non-psychoactive cannabinoids such as CBD may provide. They conclude that these cannabinoids may offer a novel therapeutic agent in the treatment of various complications of cancer.

Colon Cancer - In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines

  • University of British Columbia
  • 2014

related conditions:

Cancer

In this study, researchers looked into the role non-psychoactive cannabinoids such as CBD may play in helping to treat and manage symptoms of prostate cancer and related therapies. Their research found that CBD is a potent inhibitor of cancer cell growth, and notably is significantly less potent in non-cancer cells. Their research concludes that CBD and other non-psychoactive cannabinoids may help treat other forms of cancer as well.

Colon Cancer - Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent

  • Texas A&M University
  • 2011

related conditions:

Cancer

The researchers wanted to test the hypothesis that the anticancer activity of cannabinoids is linked to the induction of phosphatases. The team found that CBD inhibited cell growth and induced apoptosis. While cannabinoid receptor agonists induce phosphatases and apoptosis in cancer cells, this effect was ligand-dependent and must be studied further.

Colon Cancer - Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer

  • University of Naples Federico II
  • 2012

related conditions:

Cancer

This study investigates the potential chemopreventive effects of CBD on colon cancer in mice models. They believe CBD’s antioxidant, anti-inflammatory effects, along with the ability to prevent enzymatic degradation, are all key to helping cancer patients. Researchers found that CBD helped protect DNA from oxidative damage, increased endocannabinoid levels, and reduced cell proliferation.

Colon Cancer - Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol

  • University of Naples Federico II
  • 2014

related conditions:

Cancer

The team of researchers investigated the impact of CBD on colorectal cancer cell proliferation. They found that CBD reduced cell proliferation in tumoral but not healthy cells. This highlights the suggested "selective nature" of CBD. Researchers conclude their results may be beneficial in researching cannabis-based drugs for the treatment of cancer.

CBD Research That Might Be Useful for Symptoms of Colon Cancer

potencial impact research overview

Anxiety - Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

  • University of Melbourne, Australia
  • 2013

related conditions:

Anxiety

A comprehensive review of all the plant-based medicine which has had both preclinical and human clinical trials conducted about their anxiolytic-like effect. An analysis of over 1500 papers identified 21 plants which had been adequately tested, with one of the most successful of these plants found to be CBD enriched Cannabis species.

Inflammation - Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice

  • Tongji University School of Medicine
  • 2013

related conditions:

Inflammation

A study of mice concluded CBD has significant anti-inflammatory effects. The researchers also saw evidence that the expression of the GPR55 receptor was improved after starting on CBD. Treatment with CBD was shown to significantly decrease the levels of several inflammation-related chemicals in test subjects.

Nausea - Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews

  • Palo Alto University, CA, USA
  • 2017

related conditions:

Nausea

CBD was shown to significantly suppress vomiting in lab rats and shrews. Researchers used another substance, known as cannabigerol (CBG) to reverse this suppression. Moderate doses of CBG and CBD are opposing each other at the 5-HT1A receptor, which is known to play an essential role in regulating nausea.

Colon Cancer & CBD Research Overview

Not long ago, CBD was still the overshadowed little brother of THC. However, over the last 15-20 years, there has been an explosion in research suggesting a wide range of possible applications for the cannabinoid. One condition which CBD is shown to benefit potentially is colon cancer.

Some researchers believe the antioxidant and antiinflammatory effects of CBD are incredibly beneficial for those with colon cancer. Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer suggests CBD helps protect DNA from oxidative damage. They also found it could reduce the proliferation of cancer cells.

Another report, called Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol, also investigated the effect of CBD treatment on colon cancer cell proliferation. They observed a highly selective nature of CBD to target cancer cells without damaging healthy ones.

Some reports have shown CBD’s ability to induce apoptosis of both colon and prostate cancer cells. For instance, the team behind Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent showed cannabinoid receptor agonists, such as CBD, induced ligand-dependent phosphatases and apoptosis of cancer cells. More research is required to uncover precisely how this process works.

Given the apparent connection between colon and prostate cancer noted in previous research, some experts believe their possible relationship needs to be explored further. In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines wanted to determine the role CBD plays in controlling different cancer symptoms. The team highlighted the power of CBD to inhibit cancer cell growth, but not healthy cells.

Towards the use of non-psychoactive cannabinoids for prostate cancer analyzed the ability of CBD to reduce the suffering of cancer patients during palliative care. While THC can provide many of the same benefits, it’s often not an ideal choice because of the psychoactive side effects. Researchers noted the ability of CBD to provide a novel therapeutic agent in the treatment of various forms of cancer.

CBD can also benefit those living with colon cancer in several less direct ways. For example, anxiety is a pervasive problem that those facing a cancer diagnosis deal with. That said, CBD is a powerful plant-based medication for this problem. In fact, Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence, looked at over 1500 papers before crowning CBD the single best plant-based anxiety med.

Inflammation associated with colon cancer can be a painful issue. However, CBD is a known treatment for inflammation throughout the body. According to reports such as Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice, interaction with the GPR55 receptor results in a dramatic reduction of inflammation-causing chemicals in the system.

Nausea is another prevalent problem for those on various cancer treatments. That said, cannabidiol is known to limit this issue thanks to a selective effect. Studies, including

Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews, have shown CBD can significantly reduce the frequency and severity of nausea thanks to an interaction with the 5-HT1A receptor.

Best CBD for Colon Cancer

Diamond CBD Full Spectrum Honey Tincture (2500mg)

Diamond CBD Full Spectrum Honey Tincture (2500mg)

description

These tasty new honey tinctures are made of 100% all-natural honey, presenting a delicious addition to how to deliver you with the ideal amount of CBD. Available in strengths ranging from 25mg to 3500mg, add it to your morning coffee, tea, or just use it throughout the day to sweeten up every moment while enjoying all of the awesome benefits that CBD offers.

$128.00
  • CBD Per Serving: 83.33mg
  • Number Of Servings: 30
  • Cost Per Serving: $4.27
  • Cost Per/mg of CBD: $0.05
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advantages

  • Honey Flavor
  • Control Over Dosing
  • All Natural Ingredients
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.24 125.0 $7.17
Mid Dosage (100 mg/day) 1.20 25.0 $35.84
High Dosage (250 mg/day) 3.00 10.0 $89.60

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Everyday Optimal CBD Oil Tincture (4000mg)

Everyday Optimal CBD Oil Tincture (4000mg)

description

CBD oil comes in many forms and potencies, but we haven’t seen any product sold by our competitors as powerful as our 4000mg cbd oil tincture. We make this powerful hemp oil product for people who demand fast, sure-fire relief from severe symptoms.

$289.99
  • CBD Per Serving: 133.33mg
  • Number Of Servings: 30
  • Cost Per Serving: $9.67
  • Cost Per/mg of CBD: $0.07
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advantages

  • Fast Effective Relief
  • Zero THC
  • Made In USA
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.15 200.0 $10.15
Mid Dosage (100 mg/day) 0.75 40.0 $50.75
High Dosage (250 mg/day) 1.88 16.0 $126.87

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NoteCBD Tincture (250mg)

NoteCBD Tincture (250mg)

description

Support your health and wellness with CBD-infused tinctures specifically formulated for human consumption. This tincture is made with full spectrum hemp oil, MCT oil, and essential oils.

$45.00
  • CBD Per Serving: 8.33mg
  • Number Of Servings: 30
  • Cost Per Serving: $1.50
  • Cost Per/mg of CBD: $0.18
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advantages

  • Full Spectrum Extract
  • Lab Certified
  • Made In USA
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 2.40 12.5 $25.21
Mid Dosage (100 mg/day) 12.00 2.5 $126.05
High Dosage (250 mg/day) 30.01 1.0 $315.13

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Suggested CBD Dosage for Colon Cancer

Dosage Per Day

Low

20 mg

Mid

100 mg

High

250 mg

One question we seem to get all the time is how much CBD is needed to treat a given problem. We really wish that things were just this simple. If it were, we would have a master list of all the conditions CBD is known to improve and how much is needed for each one. However, to determine precisely how much you need to treat yourself, you’re going to have to experiment with different things.

While we can’t offer you the exact answer, we do have the tools to get you started correctly. Reports indicate that CBD can significantly reduce the size and spread of cancer cells in the body. They concluded it’s very well tolerated, with upwards of 700mg a day not leading to any issues. Ultimately, they believe starting with between 20-40mg and working your way up from there by increments of 10mg is the best way to feel things out.

It’s not uncommon for people to forget that CBD isn’t totally legal across the country yet. Especially when you see it in chic cafes in most major cities, it can feel as normal as anything else. However, if you plan on traveling soon, be sure to look into the local laws before taking your CBD. Some places even still treat CBD and THC to be virtually the same.

We should also take the time to mention that not every CBD product out there is THC free. Some of these CBD products specifically keep THC in the mix to bolster the impact it has on many conditions, including tumor size. That said, if you aren’t able to be impaired, you have to ensure you only buy THC-free products.

Please consider leaving your experience here for more people to learn from and build off of. With all of the mountains of conflicting reports out there, it can be very tough to get a handle on things. We want to provide a place for all CBD users to trade experience and learn more about what CBD has to offer without having to do all the leg work themselves. This is a fight worth joining, and we need every positive voice we can gather.

Tracking CBD Effectiveness For Colon Cancer

A lot of people just starting out on CBD may find it difficult to tell how well it’s working. While it can be quite discouraging, don’t feel like you’re alone. Most people will face this problem to some degree, given the relatively subtle impact CBD has.

One thing we’ve watched help many people find their ideal regimen is keeping a simple journal of their experiences. It can sound like a big undertaking, but all it requires is writing down how much CBD you took that day and what your symptoms were. For many, all it takes is a few weeks of this before they start to know exactly how well CBD is helping relieve their complications.

Everyone’s system is unique and could require a slightly different plan to maximize effectiveness. At the end of the day, what’s perfect for one person may not be quite as effective for another. That’s why it’s so important to pay attention to your body and adjust as you go.

Many users ask if they have to keep a journal to get the most out of their CBD. While it’s entirely possible to get everything you’re looking for without a journal, nothing will increase the likelihood as quickly as this simple trick.

Anyone who decides to track their progress taking CBD should consider leaving that experience here for newcomers. Not having trustworthy, user-generated information can be really scary, especially in the face of a cancer diagnosis. All it takes is a couple of minutes of your time to leave a description of your experience along with a score for how well it improved your anxiety, inflammation, or nausea symptoms.

Written By
John Mace Alois is lead content creator at the Did CBD Work? project. He’s analyzed over 400 research papers related to Cannabidiol and helped publish over 55 works related to different conditions for the project. He majored in Cultural Anthropology, with a minor in English, from the University at Albany. He is an avid collector of art supplies and refurbishes old furniture in his spare time.

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