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Endocrine Cancer overview

Endocrine cancer is a broad category, including both neuroendocrine tumors and cancer of any of the endocrine system organs, such as the thyroid, adrenal glands, pituitary glands, and more. These rare forms of cancer are very complex and can be highly varied, making understanding them more of a challenge for researchers. Since they impact the production and regulation of hormones, these conditions can have a significant impact on many aspects of daily life.

Given the wide range of possible trajectories, endocrine cancers don’t always present with signs and symptoms in the early stages. The symptoms will be highly dependent on where the tumor is and whether or not it’s producing excess hormones. That said, many will experience general signs which include a painful, growing lump under the skin, always feeling tired, or unexpected weight loss.

Endocrine cancers that cause excess hormones produce an ever wider range of symptoms. These include diarrhea and frequent urination, excessive thirst, flush or rashed skin, dizziness, and uncontrollable tremors.

While the exact cause of most endocrine cancers isn’t currently known, we do know the vast majority begin in neuroendocrine cells. These specific types of cells are similar to nerve and hormone-producing cells, and they’re found throughout the body. This means endocrine cancer can occur anywhere.

Some types of endocrine cancers are extremely slow-developing and have little risk of metastasizing rapidly. That said, other forms are quite aggressive and are known to spread quickly and destroy healthy cells everywhere it goes. This metastasizing is a significant complication of any cancer, but where endocrine cancer spreads highly depends on where it originated.

The primary risk factor for developing endocrine cancer is your genetic background. For example, the people with the highest risk are those who have inherited certain conditions such as multiple endocrine neoplasia types 1 and 2 or Von Hippel-Lindau disease. Other issues that can increase your odds of developing endocrine cancer include tuberous sclerosis and neurofibromatosis.

Endocrine cancers of all types are relatively rare. Even the most common type, thyroid cancer, only affects an estimated 64,000 people a year. However, taken together, there are still hundreds of thousands, if not more, people suffering from some type of endocrine cancer. Given the full range of different forms, the outlook is also quite varied. Some examples of endocrine tumors are incredibly treatable, while others can be very challenging to mitigate.

Endocrine cancers of all kinds are a severe diagnosis that needs to be brought under control as soon as possible. If you have any concerns that you or a loved one could be facing a new cancer diagnosis, please don’t wait to talk to your doctor. Only they can fully diagnose the problem and get you on the right path forward.

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Table of Contents

CBD Research For Endocrine Cancer

potencial impact research overview

Endocrine Cancer - Endocannabinoids in endocrine and related tumours

  • University of Salerno
  • 2008

related conditions:

Cancer - Endocrine

In this review, researchers go over currently available data to better understand the endocannabinoid system’s involvement in a variety of functions and physiopathological conditions. The authors highlight recent evidence indicating that endocannabinoids influence the proliferation of a number of endocrine-related cancers, displaying antitumoral properties. The review concludes that endocannabinoids can inhibit cancer cell growth, as well as the invasion and metastasis of thyroid, breast, and prostate cancers.

Endocrine Cancer - A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells

  • National Taiwan University
  • 2008

related conditions:

Cancer - Endocrine

Research has repeatedly demonstrated the antitumoral and anticancer properties of CBD. In this study, researchers explore cellular events and sensitivity to CBD-induced apoptosis in various forms of cancer. The experiment showed that CBD-induced apoptosis triggered a gradual diminishment in cellular thiols. Their results demonstrated that multiple cancers were susceptible to CBD-induced apoptosis, with reactive oxygen species playing a critical role in apoptosis induction.

Endocrine Cancer - Cannabinoids in pancreatic cancer: Correlation with survival and pain

  • Heidelberg University
  • 2007

related conditions:

Cancer - Endocrine

In this study, researchers evaluate the immunoreactivity of the endocannabinoid system itself and in relation to various cancers. The authors noted a significant relationship between endocannabinoid receptor expression and immunoreactivity. Their results demonstrate the alleviative and analgesic properties of cannabinoids, showing promise as a potential therapeutic agent in the treatment of cancer.

Endocrine Cancer - Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma

  • King Faisal Specialist Hospital and Research Center
  • 2007

related conditions:

Cancer - Endocrine

Researchers in this study sought to identify the role the endocannabinoid system plays in inducing apoptosis in various forms of cancer. Their study demonstrated both the antitumoral and anticancer properties of cannabinoids and the role of the endocannabinoid system in metabolic regulation. The authors conclude that CB2 agonists may serve as a novel anticancer agent thanks to its antitumor properties and lack of psychotropic side-effects.

CBD Research That Might Be Useful for Symptoms of Endocrine Cancer

potencial impact research overview

Anxiety - Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

  • University of Melbourne, Australia
  • 2013

related conditions:

Anxiety

A comprehensive review of all the plant-based medicine which has had both preclinical and human clinical trials conducted about their anxiolytic-like effect. An analysis of over 1500 papers identified 21 plants which had been adequately tested, with one of the most successful of these plants found to be CBD enriched Cannabis species.

Inflammation - Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice

  • Tongji University School of Medicine
  • 2013

related conditions:

Inflammation

A study of mice concluded CBD has significant anti-inflammatory effects. The researchers also saw evidence that the expression of the GPR55 receptor was improved after starting on CBD. Treatment with CBD was shown to significantly decrease the levels of several inflammation-related chemicals in test subjects.

Nausea - Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews

  • Palo Alto University, CA, USA
  • 2017

related conditions:

Nausea

CBD was shown to significantly suppress vomiting in lab rats and shrews. Researchers used another substance, known as cannabigerol (CBG) to reverse this suppression. Moderate doses of CBG and CBD are opposing each other at the 5-HT1A receptor, which is known to play an essential role in regulating nausea.

Endocrine Cancer & CBD Research Overview

It wasn't long ago that we didn't know much about the power of CBD. While some of its more well-established uses have been known in smaller groups for a while, the last 15 years of research have made a massive difference in what we know about cannabidiol. This explosion in evidence has established CBD as a potential treatment for many things, even cancer cell proliferation.

For example, the researchers behind Endocannabinoids in endocrine and related tumours reviewed all the available evidence connecting activation of the endocannabinoid system with improved health. The team highlighted reports which suggest cannabinoids, such as CBD, could impact the number and proliferation of endocrine-related cancers. While CBD was shown to inhibit cell growth, more research is needed to say anything for sure.

Another report, called Cannabinoids in pancreatic cancer: Correlation with survival and pain, backed up the immunoreactivity of the endocannabinoid system in regards to several types of cancer. They ultimately concluded that CBD offers novel alleviative and analgesic benefits in the treatment of cancer.

Studies have shown time and again how critical the endocannabinoid system is in the apoptosis of cancer cells. Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma showed the antitumoral properties of cannabinoids, such as CBD. Researchers also noted the lack of impairing effects as beneficial for treating a wide range of people.

While lots of research has concluded CBD may hold benefits for those who have endocrine cancer, we have less evidence highlighting how this occurs. One report we do have is called, A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells, and it not only demonstrates the anticancer properties of CBD but offers insight into how. The team concluded CBD-induced apoptosis gradually decreases the cellular thiols. As such, the team observed that many types of cancer could benefit from CBD treatment via oxygen reactive cells.

Outside of the direct benefits CBD can provide those with endocrine cancer, there are several more subtle advantages offered. For instance, anxiety is a very common issue to go along with a cancer diagnosis, as people face the severe illness. That said, CBD is known to be a powerful treatment for anxiety according to reports such as Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence. The researchers analyzed over 1500 reports before crowning CBD the single best plant-based anxiety med at our disposal.

Inflammation is another common problem facing people with a cancer diagnosis. While this can vary significantly depending on where the cancer is and how advanced it is, inflammation is an issue that goes hand-in-hand with cancer. However, reports on the antiinflammatory power of CBD, such as Antiinflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice, have identified interaction with the GPR55 receptor as a primary culprit behind this reduction in inflammation-related substances.

Another issue for many going through cancer treatment is nausea. While this can be a massive problem for some, even when it's only mild, it's still a lot to contend with. CBD may provide a powerful tool in the fight against this issue as reports such as Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews have shown. That team proved CBD's interaction with the 5-HT1A receptor dramatically reduces any nausea experienced.

Best CBD for Endocrine Cancer

Everyday Optimal CBD Capsules (200mg)

Everyday Optimal CBD Capsules (200mg)

description

Are you looking for something stronger than almost any CBD oil product on the market? Then you’ll love the newest addition to our high potency CBD line. With each capsule containing 200mg of pure CBD, you’ll experience all-natural, long-lasting relief for tough pain, sleep problems, anxiety, and more.

$299.99
  • CBD Per Serving: 200mg
  • Number Of Servings: 30
  • Cost Per Serving: $10.00
  • Cost Per/mg of CBD: $0.05
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advantages

  • Highest Capsule In USA
  • 100% USA Made
  • THC Free
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.10 300.0 $7.00
Mid Dosage (100 mg/day) 0.50 60.0 $35.00
High Dosage (200 mg/day) 1.00 30.0 $70.00

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Relax Full Spectrum CBD Oil (3500mg)

Relax Full Spectrum CBD Oil (3500mg)

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Relax Full Spectrum CBD Oil, available with an oil tincture dropper, delivers the ideal amount of CBD to meet all of your wellness needs. Made in the USA  from 100% high quality industrial hemp, this 3500 mg bottle of CBD is perfect for those wanting to combat stress, anxiety, and chronic pain.

$168.00
  • CBD Per Serving: 116.67mg
  • Number Of Servings: 30
  • Cost Per Serving: $5.60
  • Cost Per/mg of CBD: $0.05
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advantages

  • 100% Hemp Product
  • Made in USA
  • Full Spectrum
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.17 175.0 $6.72
Mid Dosage (100 mg/day) 0.86 35.0 $33.60
High Dosage (200 mg/day) 1.71 17.5 $67.20

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Diamond CBD Full Spectrum Honey Tincture (2500mg)

Diamond CBD Full Spectrum Honey Tincture (2500mg)

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These tasty new honey tinctures are made of 100% all-natural honey, presenting a delicious addition to how to deliver you with the ideal amount of CBD. Available in strengths ranging from 25mg to 3500mg, add it to your morning coffee, tea, or just use it throughout the day to sweeten up every moment while enjoying all of the awesome benefits that CBD offers.

$128.00
  • CBD Per Serving: 83.33mg
  • Number Of Servings: 30
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  • Cost Per/mg of CBD: $0.05
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  • All Natural Ingredients
  Servings per day Days supplied in one package Cost per week
Low Dosage (20 mg/day) 0.24 125.0 $7.17
Mid Dosage (100 mg/day) 1.20 25.0 $35.84
High Dosage (200 mg/day) 2.40 12.5 $71.68

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Suggested CBD Dosage for Endocrine Cancer

Dosage Per Day

Low

20 mg

Mid

100 mg

High

200 mg

We are asked almost every day what the perfect dosage of CBD is for a given condition. In a perfect world, this is precisely how it would work, and we would be done with it. However, things are much more complicated than that. At the end of the day, we each must refine the answer for ourselves.

Despite not having the precise answer for everyone, we can get you off on the right foot. Experts have made some exciting discoveries about CBD for cancer treatment. Research suggests CBD has anti-tumoral effects and is tolerable in upwards of 700mg per day doses. Most experts suggest starting small, between 20-40mg per day and adding or taking away 10mg every couple days until you find what works best.

We ought to mention that despite CBD being an increasingly popular choice across the country, it’s still not legal everywhere. Some places even treat THC and CBD as essentially the same thing, making it tricky to travel with. It’s not a significant problem for most, but make sure to do your research before taking CBD on your travels.

It’s also important to remember that not all CBD products are THC free. If you aren’t willing or able to be intoxicated, you must ensure to only buy THC free products. However, research also suggests that the anti-tumoral effects of CBD can be significantly bolstered by a bit of THC still in the mix.

Many people have trouble when just starting out, as there’s so much information out there. It can be pretty tricky to be sure what’s trustworthy and what’s just made up. As such, we believe the best resource we can provide is a place for users like you to leave their experiences for others to learn from. Please consider being part of the movement and helping the next generation of those suffering.

Tracking CBD Effectiveness For Endocrine Cancer

A significant problem for many people who are just starting out on CBD is determining precisely how well it’s working for them. As frustrating as this can be, it’s quite common as CBD has a relatively subtle impact even when working perfectly. This is why the absolute best thing you can do when starting CBD is simply paying attention to your body.

In the face of this issue, we suggest starting a journal and keeping track of a few basic things, such as your dosages and daily symptoms. It’s perfectly normal to feel a bit lost during your first few weeks on CBD. However, we’ve yet to find anyone who did this exercise and didn’t feel better equipped to answer if CBD works for them or not.

At the end of the day, how well CBD works for you is going to depend on your system. Even though a particular regimen may have been perfect for someone else, it may not be the most effective for you. The only way to know for sure is by trying different things and paying attention to how your body reacts.

We’re often asked if keeping a journal is completely necessary to be successful in taking CBD. While it’s entirely possible to get the results you’re after without doing this, nothing we can suggest will increase your odds more than this simple trick. You owe it to yourself to try everything to maximize your CBD before deciding how well it’s working.

Whichever way you choose to track your progress, we really hope you decide to leave that experience here for others to utilize. When first starting on CBD, it can be really daunting trying to figure out how you’re doing. So, user-generated reviews provide a welcome resource. All it takes is a brief description of your time taking CBD along with a score for how well it improved any inflammation, anxiety, and nausea.

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