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Fibromyalgia overview

Fibromyalgia is a chronic pain disease which is commonly associated with stiffness, fatigue, and pain throughout the body. We know a lot more about fibromyalgia than we used too, thanks in part to the last decade of research. For instance, we now know it’s a neurosensory disorder, which means it makes people much more sensitive to painful stimuli. The most common symptom for anyone with fibromyalgia is widespread and chronic pain. In fact, it’s so common that researchers have identified 19 specific areas of the body which are most heavily affected by the disease. This pain can range from aching, to shooting, to burning, and it can even be so bad it limits motion. Another common symptom is chronic fatigue, even with adequate amounts of sleep. Making matters worse, restful sleep is one of the most important things people with fibromyalgia can do to mitigate their symptoms. Other common symptoms include trouble thinking and remembering things, often called “fibrofog,” as well as anxiety and depression, especially with severe or untreated cases.

While we still don’t know exactly what causes it, we do know it affects ten times more women than men. The severity of symptoms is so persistent, if left untreated, it can often cause severe physical and emotional distress on patients. Doctors haven’t isolated the cause or causes, but they do have some leads. Family history seems to be a significant risk factor, as are bacterial and viral infections, such as Lyme disease or Hep C. Another possible risk factor is physical and emotional stress or injury. Even high levels of pain sensitivity chemicals in the brain and spinal cord are shown to correlate with fibromyalgia. Statistics show that approximately 10 million Americans suffer from fibromyalgia, with global numbers putting it somewhere between 3% and 6% of the population. It can be difficult for doctors to diagnose, which leads to many cases going untreated. So if you’re worried you or a loved one may have fibromyalgia, be sure to talk with your doctor. But it can be especially hard to move forward if you don’t understand what your treatment options are. So let’s take a look at what the research says.

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Table of Contents

CBD Research For Fibromyalgia

potencial impact research overview

Fibromyalgia - Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

  • GW Pharmaceuticals
  • 2088

related conditions:

Fibromyalgia

Review of the available literature suggests the introduction of CBD has a positive biochemical and pathophysiological effect on several conditions related to a clinical endocannabinoid deficiency. CBD was shown to block spinal, peripheral, and gastrointestinal discomfort and pain; most likely through a combination of decreasing inflammation and controlling dopamine production.

Fibromyalgia - Cannabis use in patients with fibromyalgia: effect on symptoms relief and health-related quality of life

  • Institut de Recerca Hospital del Mar-IMIM, Barcelona, Spain.
  • 2011

related conditions:

Fibromyalgia

Study confirms that just two hours after being administered, CBD significantly reduces pain and stiffness while simultaneously increasing relaxation and Pittsburgh Sleep Quality Index (PSQI) scores compared with control groups. Researchers also concluded a set regimen of CBD was associated with increased feelings of well-being and decreased anxiety.

Fibromyalgia - Association of herbal cannabis use with negative psychosocial parameters in patients with fibromyalgia

  • American College of Rheumatology, Atlanta, USA
  • 2012

related conditions:

Fibromyalgia

Researchers indicate CBD may be an effective treatment for pain relief. They also concluded over half of those dealing with widespread pain were also dealing with another significant diagnosis. While they indicated more research is needed to know anything for sure, the initial trends clearly show a connection between CBD and chronic pain relief.

Fibromyalgia - Cannabinoids for fibromyalgia

  • National Center for Complementary and Integrative Health, Bethesda, USA
  • 2016

related conditions:

Fibromyalgia

The review indicates taking CBD positively impacts the endocannabinoid system, which is known to have a central and peripheral effect on processing pain. The experimental and clinical data strongly suggest CBD is an extremely promising tool for reducing and regulating physiological and inflammatory pain.

Fibromyalgia - Medical Cannabis for the Treatment of fibromyalgia

  • Israel Institute of Technology, Haifa, Israel
  • 2018

related conditions:

Fibromyalgia

The report suggests CBD has a significant benefit for those dealing with chronic pain and fatigue. All test subjects reported a noticeable benefit, while a full 50% were able to stop taking another medication thanks to CBD. Meanwhile, only 30% experienced any side effects, and those were reportedly very mild.

CBD Research That Might Be Useful for Symptoms of Fibromyalgia

potencial impact research overview

Pain Relief - Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being

  • University College Of London
  • 2012

related conditions:

Pain Relief

Researchers concluded CBD significantly reduces discomfort and pain, in part, due to the interaction between two substances, PEA and anandamide. According to tests, they “act synergistically, reducing pain responses 100-fold more potently than each compound alone”.

Memory Loss - Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment

  • Institute of Psychiatry, King’s College, London, UK
  • 2012

related conditions:

Memory Loss

Research indicates pretreatment with CBD significantly decreases THC-elicited psychosis and cognitive impairment. Interestingly, the team determined CBD also significantly increased episodic memory compared with the placebo group. The findings suggest CBD helps prevent any mental health risks associated with THC alone.

Anxiety - Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

  • University of Melbourne, Australia
  • 2013

related conditions:

Anxiety

A comprehensive review of all the plant-based medicine which has had both preclinical and human clinical trials conducted about their anxiolytic-like effect. An analysis of over 1500 papers identified 21 plants which had been adequately tested, with one of the most successful of these plants found to be CBD enriched Cannabis species.

Fibromyalgia & CBD Research Overview

While many of its benefits have been known for years now, CBD has really gained a lot of popularity thanks to the growing community of users and researchers working to unlock its secrets. One of the most incredible ways CBD has been able to help is by mitigating symptoms for people with a wide variety of chronic pain disorders, especially fibromyalgia. A comprehensive review of all the available research called, Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? concluded CBD helps block spinal, peripheral, and gastrointestinal pain. While more research is needed to understand this effect better, the researchers believe this benefit is likely related to a decrease in inflammation as well as regulating dopamine production. Another theory to why CBD has increased in popularity so rapidly is the wide range of conditions it seemingly improves. A report called Association of herbal cannabis use with negative psychosocial parameters in patients with fibromyalgia found over half of those with widespread pain from fibromyalgia also suffer from another condition related to chronic pain.

For those dealing with severe fibromyalgia, discomfort and pain is often a daily battle. One of the main reasons CBD is being turned to for fibromyalgia is the known connection between the endocannabinoid system and pain regulation in the body. A review of the experimental and clinical data, called Cannabinoids for fibromyalgia makes a robust case CBD has central and peripheral effects on inflammatory pain in fibromyalgia patients. This massive benefit could be explained thanks to a report called Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. Researchers concluded the combination of two substances, anandamide and PEA act synergistically, which allows CBD to be 100-fold more effective for pain relief than if either substance was alone. But what does this mean for those dealing with fibromyalgia? Well, a report called Medical Cannabis for the Treatment of fibromyalgia makes a very strong case. They concluded CBD is so effective at treating fibromyalgia symptoms, not only did all the participants report noticeable improvements in pain, but half were able to stop taking another medication altogether thanks to CBD.

However, it’s not just chronic pain relief that fibromyalgia patients deal with. Luckily, CBD has been shown to be effective at treating many of these other symptoms. In fact, a study called Cannabis use in patients with fibromyalgia: effect on symptoms relief and health-related quality of life confirmed several of these beliefs, all at once. They found not only does CBD improve pain and stiffness while relaxing users, but it also was shown to decrease anxiety and improve Pittsburgh Sleep Quality Index scores. Looking deeper, CBD has been shown to significantly reduce cognitive impairment, another common symptom of fibromyalgia sometimes known as “fibrofog.” This evidence was published in a report called Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment. The team also concluded CBD dramatically improved episodic memory when compared with the placebo group. Many of these symptoms can be quite hard to deal with, and it’s not uncommon for fibromyalgia patients to suffer from some depression or anxiety. A comprehensive review of over 1500 reports, called Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence concluded CBD is likely the most effective plant-based medicine we have for treating anxiety.

Best CBD for Fibromyalgia

Fibromyalgia Relief CBD Capsules, 25mg CBD + Added Vitamins

Fibromyalgia Relief CBD Capsules, 25mg CBD + Added Vitamins

description

Our Fibromyalgia CBD Capsules contain over 17 essential vitamins and minerals as well as 25mg of pure CBD in each capsule with 60 capsules included in each purchase.

$129.99
  • CBD Per Serving: 25mg
  • Number Of Servings: 60
  • Cost Per Serving: $2.17
  • Cost Per/mg of CBD: $0.09
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advantages

  • 17 Added Vitamins
  • No THC, Side Effects
  • 100% USA Made
  Servings per day Days supplied in one package Cost per week
Low Dosage (10 mg/day) 0.40 150.0 $6.07
Mid Dosage (15 mg/day) 0.60 100.0 $9.10
High Dosage (25 mg/day) 1.00 60.0 $15.17

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NoteCBD Capsules (10mg)

NoteCBD Capsules (10mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$45.00
  • CBD Per Serving: 10mg
  • Number Of Servings: 30
  • Cost Per Serving: $1.50
  • Cost Per/mg of CBD: $0.15
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advantages

  • Full Spectrum
  • Lab Certified
  • Organic
  Servings per day Days supplied in one package Cost per week
Low Dosage (10 mg/day) 1.00 30.0 $10.50
Mid Dosage (15 mg/day) 1.50 20.0 $15.75
High Dosage (25 mg/day) 2.50 12.0 $26.25

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NoteCBD Capsules (25mg)

NoteCBD Capsules (25mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$95.00
  • CBD Per Serving: 25mg
  • Number Of Servings: 30
  • Cost Per Serving: $3.17
  • Cost Per/mg of CBD: $0.13
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advantages

  • Full Spectrum
  • Gluten Free
  • Lab Certified
  Servings per day Days supplied in one package Cost per week
Low Dosage (10 mg/day) 0.40 75.0 $8.87
Mid Dosage (15 mg/day) 0.60 50.0 $13.30
High Dosage (25 mg/day) 1.00 30.0 $22.17

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Suggested CBD Dosage for Fibromyalgia

Dosage Per Day

Low

10 mg

Mid

15 mg

High

25 mg

Probably the most common question we get about CBD is precisely how much should people take for their various conditions. While it would be great if we could just give a set dose for different issues, the truth is things are more complicated. Each person has a very different endocannabinoid system and will react to CBD.

What works for some, may not work for others. Even if it works for two people, the ideal dosages will likely be different. However, that doesn’t mean we can’t give you a good place to start. From there, it’s up to you to experiment a little and tease out your perfect frequency and strength of CBD for fibromyalgia.

The good news is CBD is a non-psychoactive substance, which means it doesn’t get you high like THC does. So there’s minimal risk in trying various strengths of CBD to test personal effectiveness. Arthritis.org indicates lower doses of CBD are ideal for chronic pain relief and stiffness, usually between 10-25mg per day. That said, it’s always smart to start lower, about 5-10mg. This gives your body time to adjust, as well as allow you to incrementally increase dosage until you hit that sweet spot.

CBD is famously non-reactive, but before you start on any medicine, it’s always a good idea to talk to your doctor about any possible interactions with other medications you’re on. It’s also worth mentioning that some research suggests having a bit of THC present can significantly increase many benefits of CBD.

So if you’re not having success with CBD alone, and it’s legal where you live, you may want to consider a product with a small amount of THC present. If you do, be careful; THC is psychoactive and will get you high. Whatever type of CBD product you go with, be sure to track your dosing and side effects. It can make a world of difference!

Tracking CBD Effectiveness For Fibromyalgia

One of the hardest parts about starting any new medication is knowing what to keep an eye out for. Taking CBD for fibromyalgia is no different, as it will likely take a little time before you can tell how your progress is coming. One of the things making it easier to track your progress is the nature of fibromyalgia as a chronic pain condition.

Most patients are already acutely aware of all their symptoms and how frequently they occur. This will help when you’re establishing what your ideal dose of CBD is, as a large part of this is merely paying attention to your body and keeping track of how much CBD you’re taking.

The only way to know precisely what works for you is to do some experimentation. One great way to help avoid getting your days mixed up is to keep a simple journal of your dosages and symptoms. You’d be amazed at how much an easy thing like that can speed up your journey to find the perfect routine.

Whatever you end up doing, you should seriously consider leaving your own experiences here for others on the same journey. Just leaving a simple comment could have a massive impact on someone else looking to ease their pain and increase their quality of life. Whenever you decide to leave your experience, be sure to give a score for the pain relief, decreased fatigue/sleeplessness, as well as anxiety and depression relief provided by CBD.

If we work together, we can help others avoid years of excess suffering due to fibromyalgia.

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