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Glaucoma overview

Glaucoma is a group of different conditions that damage the optic nerve, harming vision. This damage is typically caused by high levels of pressure, which place the eye and optic nerve under stress.

The damage and subsequent vision loss happen gradually, with many not even really noticing until things have progressed quite a bit. The vision loss associated with glaucoma cannot be reversed, making early detection and treatment paramount.

The signs and symptoms of glaucoma can vary significantly depending on the type and how far they’ve progressed. The two main categories of symptoms are open-angle glaucoma and acute angle-closure glaucoma.

Open-angle typically results in blind spots in your side or central vision, usually in both eyes. This will develop into tunnel vision in the later stages. Alternatively, angle-closure results in painful headaches accompanied by blurry vision. People may also experience nausea, eye pain and redness, as well as a halo effect around lights.

Other types of glaucoma include normal-tension glaucoma, pigmentary glaucoma, and childhood glaucoma. These less common forms of the condition provide interesting cases, such as how normal-tension glaucoma occurs despite a lack of internal eye pressure.

Glaucoma is caused by damage to the optic nerve, which gradually develops into blind spots. While researchers still don’t fully understand why this happens, they know that it’s typically related to increased pressure.

This increased pressure happens when there’s a buildup of the fluid that flows through the eyes. Instead of draining out as it’s meant too, via the trabecular meshwork, this fluid can’t flow out fast enough, increasing overall pressure.

The main risk factor for glaucoma is high internal eye pressure, as discussed. However, a few other things also seem to be related to higher rates of glaucoma. These include being over the age of 60, having a family history, being of African descent, having very poor eyesight, an eye injury, or prolonged use of eye drops can all increase your chances of developing glaucoma.

Glaucoma is a relatively common condition, with an estimated three million Americans living with the disease. Open-angle glaucoma is by far the more common type, with around 2.7 million of those affected by the condition having this type.

If you’re worried about you or a loved one’s eyesight, be sure to talk to a doctor as soon as possible. Only they can offer the proper testing and diagnosis. The damage caused by glaucoma cannot be reversed, making early detection and treatment extremely important. For many people, they won’t really notice anything is wrong until it’s too late.

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Table of Contents

CBD Research For Glaucoma

potencial impact research overview

Glaucoma - Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite

  • Medical College of Georgia
  • 2003

related conditions:

Glaucoma

Researchers wanted to determine how cannabinoids are able to benefit glaucoma patients. The result of the study found that cannabinoids help protect against an excessive formation of peroxynitrite. It is this excess of peroxynitrite that causes cell death behind glaucoma — the cannabinoids administered via injection to the eye and have proven an effective therapy and treatment.

Glaucoma - Cannabinoids and glaucoma

  • Aberdeen Royal Infirmary
  • 2004

related conditions:

Glaucoma

This article is an overview of the latest research, of the time, on cannabinoid treatment of Glaucoma. Their purpose is to help inform people and to promote further research of the topic. They discuss how cannabinoids can significantly lower pressure within the eyes. They also highlights CBD’s neuroprotective qualities.

Glaucoma - The treatment of glaucoma using a non-psychoactive preparation of cannabis sativa

  • University of the West Indies
  • 1978

related conditions:

Glaucoma

This study was some of the initial research into non-psychotropic cannabinoids that would result in the discovery of CBD. In this study, researchers identified a non-psychotropic preparation of sativa lowered intraocular pressure in patients with glaucoma. They concluded that there is a non-psychotropic element to sativa which garnered these impressive results.

Glaucoma - Cannabinoids for treatment of glaucoma

  • University of California
  • 2016

related conditions:

Glaucoma

This review of research concerning cannabinoids and glaucoma found interesting results. One discussed aspect was the dramatic increase in potency since the 70s/80s when the researcher first studied the potential. They believe the increase in cannabis potency could reduce its effectiveness in treating glaucoma, due to an impact on ocular blood flow. Because of this, they suggest always starting slow and building up.

Glaucoma - Cannabinoid applications in glaucoma

  • The University of the Basque Country, Spain
  • 2011

related conditions:

Glaucoma

Cannabinoids have been shown to have a significant impact on the intraocular pressure usually associated with vision problems. According to testing, activation of CB1 not only reduces pressure, but it also has a neuroprotective effect on retinal cells.

CBD Research That Might Be Useful for Symptoms of Glaucoma

potencial impact research overview

Anxiety - Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

  • University of Melbourne, Australia
  • 2013

related conditions:

Anxiety

A comprehensive review of all the plant-based medicine which has had both preclinical and human clinical trials conducted about their anxiolytic-like effect. An analysis of over 1500 papers identified 21 plants which had been adequately tested, with one of the most successful of these plants found to be CBD enriched Cannabis species.

Pain Relief - Control of pain initiation by endogenous cannabinoids

  • University of Naples Federico II
  • 1998

related conditions:

Pain Relief

Researchers concluded CBD significantly reduces discomfort and pain, in part, due to the interaction between two substances, PEA and anandamide. According to tests, they “act synergistically, reducing pain responses 100-fold more potently than each compound alone”.

Nausea - Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews

  • Palo Alto University, CA, USA
  • 2017

related conditions:

Nausea

CBD was shown to significantly suppress vomiting in lab rats and shrews. Researchers used another substance, known as cannabigerol (CBG) to reverse this suppression. Moderate doses of CBG and CBD are opposing each other at the 5-HT1A receptor, which is known to play an essential role in regulating nausea.

Glaucoma & CBD Research Overview

In a relatively short period, CBD has grown out of the shadow of THC and developed into a robust industry of its own. A lot of this growth is thanks to the research proving the ability of CBD to treat a wide variety of different conditions. One possible use of CBD that is currently gaining a lot of popularity is the treatment of glaucoma.

Researchers have begun trying to determine why CBD seems to be helpful in the treatment of glaucoma. One such study, called Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite, determined CBD could protect against the formation of excess peroxynitrite, which is known to cause cell death during glaucoma.

Other reports have found a powerful pressure reduction effect of CBD treatment. For instance, a study called, Cannabinoid applications in glaucoma Aplicaciones de los cannabinoides en glaucoma showed CBD eyedrops effectively reduced the intraocular pressure, along with other neuroprotective benefits associated with CBD.

This benefit of CBD has become well known around the glaucoma community, as even general information on the disease will sometimes now include information on CBD. This includes Cannabinoids and glaucoma, which provided an overview of the condition while noting the power of CBD to reduce pressure in the eyes and protect your brain.

Some of the earliest research on CBD’s benefit to glaucoma comes all the way from the 1970s. One report, called The treatment of glaucoma using a non-psychoactive preparation of cannabis sativa, which was originally published back in 1978, was one of the first to note the power of cannabinoids to reduce ocular pressure. It was also one of the first to identify CBD as a separate unique cannabinoid.

Other researchers have looked into how the potency of cannabis has grown over the last several decades, as well as what it means for the treatment of various conditions, including glaucoma. Cannabinoids for treatment of glaucoma noted that the effectiveness of CBD might be reduced by the dramatic increase in potency over the last 40+ years. However, they believe starting slow is the best way to mitigate this particular problem.

Other reports have shown powerful ways in which CBD can improve the lives of those with glaucoma. Pain is a common symptom of glaucoma, luckily Control of pain initiation by endogenous cannabinoids showed two of the substances related to cannabinoids, PEA and anandamide, reduce pain synergistically to increase effectiveness 100-fold.

Anxiety is another common symptom of glaucoma, as people grow worried about their ability to see the world around them. Reports like Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence, prove CBD is one of the most potent all-natural medications we have in the treatment of anxiety.

Another common symptom of glaucoma is nausea, as eyesight continues to decline. CBD has once again been shown helpful in the reduction of nausea symptoms. Reports such as, Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews, show clear evidence that CBD suppresses nausea via the 5-HT1A receptor.

Best CBD for Glaucoma

NoteCBD Capsules (10mg)

NoteCBD Capsules (10mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$45.00
  • CBD Per Serving: 10mg
  • Number Of Servings: 30
  • Cost Per Serving: $1.50
  • Cost Per/mg of CBD: $0.15
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advantages

  • Full Spectrum
  • Lab Certified
  • Organic
  Servings per day Days supplied in one package Cost per week
Low Dosage (2 mg/day) 0.20 150.0 $2.10
Mid Dosage (5 mg/day) 0.50 60.0 $5.25
High Dosage (10 mg/day) 1.00 30.0 $10.50

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NoteCBD Capsules (25mg)

NoteCBD Capsules (25mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$95.00
  • CBD Per Serving: 25mg
  • Number Of Servings: 30
  • Cost Per Serving: $3.17
  • Cost Per/mg of CBD: $0.13
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advantages

  • Full Spectrum
  • Gluten Free
  • Lab Certified
  Servings per day Days supplied in one package Cost per week
Low Dosage (2 mg/day) 0.08 375.0 $1.77
Mid Dosage (5 mg/day) 0.20 150.0 $4.43
High Dosage (10 mg/day) 0.40 75.0 $8.87

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Pure CBD Oil Capsules (15mg)

Pure CBD Oil Capsules (15mg)

description

Every Day Optimal Soft Gel PCR Hemp Oil Capsule contains 15mg pure CBD from our proprietary high CBD strain of hemp.

$59.99
  • CBD Per Serving: 15mg
  • Number Of Servings: 30
  • Cost Per Serving: $2.00
  • Cost Per/mg of CBD: $0.13
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advantages

  • Easy Capsule Form
  • No GMO
  • All Natural
  Servings per day Days supplied in one package Cost per week
Low Dosage (2 mg/day) 0.13 225.0 $1.87
Mid Dosage (5 mg/day) 0.33 90.0 $4.67
High Dosage (10 mg/day) 0.67 45.0 $9.33

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Suggested CBD Dosage for Glaucoma

Dosage Per Day

Low

2 mg

Mid

5 mg

High

10 mg

By far, the most common question we get is how much CBD needs to be taken to help a given condition. While in an ideal world, we could simply provide this answer and be done with it, the human body is much more complex than that and may require a particular regimen.

However, that doesn't mean we can't give you a solid starting point to build off from. According to reports, small doses of CBD are ideal when looking to reduce ocular pressure, even as low as 5mg. So definitely start slow and only work up over time.

CBD has become an extremely common thing across the country, but that doesn't mean that it's legal everywhere. In fact, some places still treat CBD and THC as the same, meaning it can be very illegal to possess. This means it's important to always double-check local laws before traveling if you intend to bring your CBD.

It's also important to keep in mind that not all CBD products are going to be THC free. Some people find that a bit of THC still mixed with the CBD product can enhance the desired effects. However, if you're someone who doesn't want to risk getting high, be sure only to buy 100% CBD products.

Whichever way you end up taking CBD or tracking your progress, we hope that you decide to leave your experiences here for new users to learn from. The more information that we can share with each other, the more well informed we all can be.

Tracking CBD Effectiveness For Glaucoma

One of the things that tend to be the most difficult for people just starting out on CBD is understanding how well it's working for you. This can be really frustrating for people who are just looking for a bit of relief, but you're not alone. CBD's effect is relatively subtle, even when working properly, so it can take some time and attention until you zero in on the ideal routine. This is definitely the case for glaucoma, as it may simply slow the progression of symptoms, making it hard to pinpoint.

We always suggest that people beginning a regimen of CBD grab a journal to keep track of their progress. All it takes is writing down your daily doses, along with the subsequent symptoms experienced. After a short period, most people feel much better equipped to answer the question of if CBD works for them.

Each person has a unique system and may require a slightly different routine. The best thing you can do is try different things at first, and make a note of which ones were more effective for you.

Many people wonder if keeping a journal is totally necessary for success. And while it's perfectly possible to find success with CBD without a journal, nothing will make that transition easier or more natural.

If you do choose to track your progress taking CBD, we sincerely hope you decide to leave those experiences here for others to learn from. With just a brief description of your time taking CBD, and a score for how it improved your pain, anxiety, or nausea, you can make a huge difference for someone else. By working together, we can build the best resource for any who wants to know if CBD will work for them.

Written By
John Mace Alois is lead content creator at the Did CBD Work? project. He’s analyzed over 400 research papers related to Cannabidiol and helped publish over 55 works related to different conditions for the project. He majored in Cultural Anthropology, with a minor in English, from the University at Albany. He is an avid collector of art supplies and refurbishes old furniture in his spare time.

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