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People who struggle with Kidney Disease, rated CBD highly in helping ease their condition.

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Kidney Disease overview

Chronic kidney disease, sometimes known as chronic kidney failure, is a condition that progressively decreases the kidney’s ability to function. In a healthy person, the kidneys filter waste and other fluids from the blood to be excreted in the urine. However, those with kidney disease lose the ability to properly filter waste material, which leads to dangerous levels of various substances building up.

In the early stages of kidney disease, most people experience very few or no symptoms at all. This means that for many, they won’t even know they have a problem until it’s reached a relatively severe point.

Treatment plans for kidney disease typically revolve around slowing the progression of the condition. This primarily means limiting damage to the kidneys by controlling substance intake. When kidney disease reaches a critical point, known as end-stage kidney failure, it becomes fatal without regular dialysis or a transplant.

Signs of kidney disease tend to develop slowly, and thanks to the ability of kidneys to adapt, most people won’t notice anything until severe damage has already occurred. These symptoms include nausea, loss of appetite, fatigue, trouble sleeping, cramps, and high blood pressure. Another thing that makes kidney disease tough to diagnose at first is the fact its symptoms are usually nonspecific.

The exact causes behind kidney disease aren’t currently understood. However, researchers know quite a bit about conditions and illnesses that are known to lead to kidney disease. These include both type 1 and 2 diabetes, high blood pressure. That said, other conditions such as inflammation of the kidney, polycystic kidney disease, prolonged obstruction of the urinary tract, recurrent kidney infection, and more can all result in chronic kidney disease.

The primary risk factors of kidney disease, outside of the listed conditions, include being a smoker or being obese. Kidney disease is also known to affect more people of African, Native American, or Asian descent than other backgrounds. Family history and older age are two more common risk factors that may raise your chances of developing this disorder.

According to reports, kidney disease affects around 37 million people across the US or about 15% of the adult population. Estimates suggest 1 in 3 people are at risk of developing kidney disease at some point. What’s worse, approximately 90% of those with the disorder aren’t currently aware of it.

If you think that you or a loved one could be dealing with kidney disease, it’s vital to talk to your doctor as soon as possible. Only they can accurately diagnose conditions such as kidney disease, and set you on the path to managing your symptoms.

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Table of Contents

CBD Research For Kidney Disease

potencial impact research overview

Kidney Disease - Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death

  • Zhejiang University
  • 2009

related conditions:

Kidney Disease

This study looks at the impact CBD may play in helping reduce oxidative and nitrosative stress induced by nephrotoxicity. Using rat models, researchers noted that CBD treatment notably attenuated cisplatin-induced nitrosatve/oxidative stress, as well as inflammation, kidney cell death, and it even improved renal function. The authors concluded that their results suggest CBD may hold promise as a protective treatment against cisplatin-induced nephrotoxicity.

Kidney Disease - Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay

  • Nephrology and Urology Institute
  • 2018

related conditions:

Kidney Disease

This study sought to assess the safety, efficacy, and possible drug interactions in kidney transplant patients treated with CBD to alleviate their chronic pain. Researchers assessed patients receiving CBD treatment while measuring creatinine, blood count, liver function, live enzymes, and drug levels the entire trial. During a follow-up, researchers found that CBD was not only well-tolerated in patients, but there were no severe adverse effects observed as well.

Kidney Disease - Is There a Legitimate Role for the Therapeutic Use of Cannabinoids for Symptom Management in Chronic Kidney Disease?

  • University of Alberta
  • 2011

related conditions:

Kidney Disease

Researchers looked into the symptomatic burden faced by those with chronic kidney disease, and the potential use cannabinoids may play in helping. Researchers note the current dependance on opioids many healthcare providers and patients are forced toward due to a lack of novel therapies available. Current data indicates CBD may hold promise as a novel therapeutic approach for the pain and symptom management of chronic kidney disease.

Kidney Disease - The emerging role of the endocannabinoid system in the pathogenesis and treatment of kidney diseases

  • The Hebrew University of Jeruselum
  • 2015

related conditions:

Kidney Disease

This review focuses on the role of the endocannabinoid system in kidney function and various diseases that contribute directly to the development of renal pathways. The author notes that the development of peripherally-restricted CB1 antagonists may offer a novel pharmacological treatment for renal diseases. The review concludes that these new antagonists, as well as new CB2 agonists, may offer therapeutic benefits in attenuating kidney injury as well as promoting tissue repair.

CBD Research That Might Be Useful for Symptoms of Kidney Disease

potencial impact research overview

Inflammation - Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice

  • Tongji University School of Medicine
  • 2013

related conditions:

Inflammation

A study of mice concluded CBD has significant anti-inflammatory effects. The researchers also saw evidence that the expression of the GPR55 receptor was improved after starting on CBD. Treatment with CBD was shown to significantly decrease the levels of several inflammation-related chemicals in test subjects.

Nausea - Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews

  • Palo Alto University, CA, USA
  • 2017

related conditions:

Nausea

CBD was shown to significantly suppress vomiting in lab rats and shrews. Researchers used another substance, known as cannabigerol (CBG) to reverse this suppression. Moderate doses of CBG and CBD are opposing each other at the 5-HT1A receptor, which is known to play an essential role in regulating nausea.

Endocrine Disorders - Chronic administration of cannabidiol to healthy volunteers and epileptic patients

  • Pharmacology
  • 1980

related conditions:

Endocrine Disorders

In this study, researchers administered CBD to volunteers dealing with secondary generalized epilepsy; Another group of volunteers received a placebo. Patients were administered 200-300mg daily of either CBD or placebo for as long as 4 ½ months. Half of the participants in the CBD group remained seizure-free throughout the experiment, with ¾ of the remaining participants demonstrating at least partial improvement in managing convulsions.

Kidney Disease & CBD Research Overview

There has been an explosion in CBD research over the last 20 years, producing a ton of data on all the many benefits cannabidiol can provide. While many know about the well-reported things CBD can do, such as reducing seizures, the latest research has proven that those living with conditions such as kidney disease also stand to gain a lot by starting a regimen of CBD.

One such report, called Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death showed treatment with CBD could significantly reduce oxidative stress and inflammation associated with kidney disease. The authors believed their data provides plenty of foundation for further study of the impact CBD has on cisplatin-induced nephrotoxicity.

Studies looking into the safety and efficacy of CBD to treat kidney disease have also produced promising results. Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay assessed patients who had taken CBD to treat their pain after a kidney transplant. After measuring creatinine, blood count, liver function, live enzymes, and more, the team concluded CBD was well tolerated by patients and wasn't shown to cause any adverse effects.

Other researchers have been focused on the power of CBD to help control symptoms of chronic kidney disease, such as the authors of Is There a Legitimate Role for the Therapeutic Use of Cannabinoids for Symptom Management in Chronic Kidney Disease? Noting the current dependence on opioid medications, the team suggests CBD could be part of a viable treatment plan to reduce pain and manage other symptoms.

Reviews of the available information, such as The emerging role of the endocannabinoid system in the pathogenesis and treatment of kidney diseases, has identified specific ways in which CBD is beneficial. Researchers observed that peripherally restricted CB1 and CB2 antagonists could provide powerful relief from kidney damage by promoting tissue repair.

There's also a growing pile of peer-reviewed evidence not specifically concerned with kidney disease, which nonetheless provides robust evidence about CBD's impact on kidney disease symptoms. For example, CBD is well documented to help reduce inflammation across the body. Reports such as Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice have identified the GPR55 receptors as central to this benefit provided by CBD. Treatment with cannabidiol dramatically lowered many inflammation-related substances in the system.

Another common problem for those living with kidney disease is nausea and vomiting. Luckily, CBD is a powerful anti-nausea medication according to a growing number of studies. Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews, concluded that CBD has a powerful impact on the 5-HT1A receptor, which is known to help regulate nausea.

Another issue that those with kidney disease sometimes face is seizures. However, CBD is probably most well known for its ability to control seizures of a wide variety. Reports such as Chronic administration of cannabidiol to healthy volunteers and epileptic patients indicate a daily regimen of CBD can dramatically improve seizures, with half of their participants reporting total freedom over the nearly five-month-long trial.

Best CBD for Kidney Disease

NoteCBD Capsules (25mg)

NoteCBD Capsules (25mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$95.00
  • CBD Per Serving: 25mg
  • Number Of Servings: 30
  • Cost Per Serving: $3.17
  • Cost Per/mg of CBD: $0.13
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advantages

  • Full Spectrum
  • Gluten Free
  • Lab Certified
  Servings per day Days supplied in one package Cost per week
Low Dosage (25 mg/day) 1.00 30.0 $22.17
Mid Dosage (50 mg/day) 2.00 15.0 $44.33
High Dosage (120 mg/day) 4.80 6.3 $106.40

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Pure CBD Oil Capsules, (50mg)

Pure CBD Oil Capsules, (50mg)

description

Every Day Optimal Soft Gel PCR Hemp Oil Capsule contains 50mg of pure CBD.

$119.99
  • CBD Per Serving: 50mg
  • Number Of Servings: 30
  • Cost Per Serving: $4.00
  • Cost Per/mg of CBD: $0.08
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advantages

  • Easy Capsule Form
  • All Natural
  • GMP Compliant
  Servings per day Days supplied in one package Cost per week
Low Dosage (25 mg/day) 0.50 60.0 $14.00
Mid Dosage (50 mg/day) 1.00 30.0 $28.00
High Dosage (120 mg/day) 2.40 12.5 $67.19

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NoteCBD Tincture (250mg)

NoteCBD Tincture (250mg)

description

Support your health and wellness with CBD-infused tinctures specifically formulated for human consumption. This tincture is made with full spectrum hemp oil, MCT oil, and essential oils.

$45.00
  • CBD Per Serving: 8.33mg
  • Number Of Servings: 30
  • Cost Per Serving: $1.50
  • Cost Per/mg of CBD: $0.18
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advantages

  • Full Spectrum Extract
  • Lab Certified
  • Made In USA
  Servings per day Days supplied in one package Cost per week
Low Dosage (25 mg/day) 3.00 10.0 $31.51
Mid Dosage (50 mg/day) 6.00 5.0 $63.03
High Dosage (120 mg/day) 14.41 2.1 $151.26

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Suggested CBD Dosage for Kidney Disease

Dosage Per Day

Low

25 mg

Mid

50 mg

High

120 mg

The most common question we ever get is how much CBD needs to be taken to deal with various conditions. While we wish that we could provide a simple answer for everyone who needs it, the truth is a bit more complicated. What it takes to find out exactly how much CBD you need is good old fashioned experimentation.

That said, we can offer a solid starting point for you to begin your search for an ideal regimen. According to reports, around 50mg of CBD per day is a stable place to start. If possible, researchers suggest splitting your dosage in half and taking one dose in the morning and the other at night.

It’s important to mention that while CBD is legal in most places, it’s still treated differently in certain areas. In fact, some places even treat CBD and THC as essentially the same, making it illegal to have. Luckily, all it takes to ensure your safety is a bit of research before travel.

Some people don’t realize that not all CBD products are THC-free. In fact, some people believe CBD products that still contain a bit of THC are more effective. While there is evidence backing up this belief, but if you don’t want to run the risk of getting high, you must avoid these products. Ensure you’re only opting for THC-free products.

No matter which way you decide to take your CBD, we hope you choose to leave your experiences here for newcomers to use. Most people find it hard to understand what’s best when first starting out, so the more insight, the better. We firmly believe the more experience we have to draw from, the easier it is to get your footing with CBD.

Tracking CBD Effectiveness For Kidney Disease

Something that tends to be difficult for people who are just starting out with CBD is understanding how well it’s working for them. Most people find it very frustrating, but it’s important to know that you’re not alone. CBD has a relatively subtle impact, even when working correctly, so don’t be worried if it takes extra time to get a firm grasp on things.

The first thing we recommend for anyone is keeping a journal to track progress. All it requires is tracking your daily doses, along with the subsequent symptoms. Most people are amazed by how much of a difference this simple trick can make to their grasp of the situation.

Everyone has a different endocannabinoid system, and so what works for one person may be too much, or not enough for another. The only thing that will ensure you know whether or not CBD works for you is by trying it for yourself and paying attention to your body.

Keeping a journal can feel like an unnecessary chore for some people, but we assure you nothing is as easy to do and impactful. Of course, you can be successful in taking CBD without keeping a journal, but if you want to give it every chance it has, this is the primary thing we suggest.

Anyone who does decide to track their progress taking CBD should seriously consider leaving their experience here for others to have. When you’re first starting out, it can be beneficial to have a bit of insider knowledge from someone further along than yourself. All it takes is a brief overview of your experience taking CBD, along with a score for how well it improved your inflammation, nausea, and seizures. Five minutes of your time can make a world of difference for someone else.

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