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Metabolic Syndrome overview

Metabolic syndrome refers to a group of conditions that occur together and significantly increase someone’s risk of developing heart disease, stroke, and type-2 diabetes. The primary issues that constitute metabolic syndrome include high blood pressure and blood sugar, obesity, as well as abnormal cholesterol and triglyceride levels.

Individuals with only one of these problems probably don’t have metabolic syndrome; however, each one compounds and dramatically increases the chances of further complications. The more you have, the higher your chances of developing type-2 diabetes and heart disease. As such, lifestyle changes are paramount when facing metabolic syndrome.

Identifying metabolic syndrome can be somewhat challenging, as many of the associated disorders don’t have any clear signs or symptoms. One sign that is quite clear is obesity, particularly fat accumulation around the waist. Another potential indicator is symptoms of diabetes, which can present themselves when blood sugar gets high. These include fatigue, blurred vision, as well as increased drinking and urination.

The cause of metabolic syndrome is linked to the various conditions associated with it. That said, one that seems particularly closely linked is being overweight or inactive. Another potential cause is insulin resistance, which results in raised blood sugar despite the body churning out lots of insulin in an attempt to lower it.

The primary risk factors of developing metabolic syndrome include age, ethnicity, weight, and having other diseases. For instance, the risk of metabolic syndrome grows with age and is higher for Hispanic people, especially women, than other racial groups. As discussed, obesity significantly increases the chances of having diabetes or other conditions that lead to metabolic syndrome.

However, other less well-known factors, such as having had nonalcoholic fatty liver disease, polycystic ovaries, or even sleep apnea, can all increase the chances of developing metabolic syndrome. Lifestyle changes are the best way to combat the risk of metabolic syndrome, as 30 minutes of activity, a balanced diet, and not smoking are known to lower risk.

Metabolic syndrome is terribly common, with the American Heart Association estimating 47 million people have it in the US alone; That’s nearly one out of every six people. The good news is that most of the more significant issues associated with metabolic syndrome can be controlled with lifestyle changes.

If you’re concerned that you or a loved one could be living with metabolic syndrome, be sure to talk to a doctor as soon as you can. Only they can accurately diagnose any related issues and get you on the right path to positive change.

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Table of Contents

CBD Research For Metabolic Syndrome

potencial impact research overview

Metabolic Syndrome - The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults

  • American Journal of Medicine
  • 2013

related conditions:

Metabolic Syndrome

In this study, researchers sought to investigate the relationship between using cannabinoids, such as CBD, and fasting insulin, glucose, and insulin resistance. They used a combination of self-reported assessments and blood testing on a pool of 4657 participants. The team ultimately found cannabinoid use was associated with 16% lower fasting insulin levels, as well as significant associations between marijuana use and smaller waist circumferences.

Metabolic Syndrome - The potential use of cannabidiol in the therapy of metabolic syndrome

  • Budapest Institute of Pharmacology
  • 2012

related conditions:

Metabolic Syndrome

This report reviews the potential use of CBD in the therapy and treatment of those currently living with metabolic syndrome. The author highlighted CBD’s immunomodulating effect, ability to alleviate hyperphagia without side effects, and potential in fighting ischaemic diseases. They concluded CBD administration might be beneficial in adjuvant therapy due to a lack of side effects.

Metabolic Syndrome - Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes

  • National Research Council, Italy
  • 2011

related conditions:

Metabolic Syndrome

This report highlights the novel aspects of cannabinoids, with an emphasis on the biological effects of plant cannabinoids and endocannabinoid receptor antagonists in diabetes. The authors note the role that the endocannabinoid system plays in metabolism, and that endocannabinoid dysregulation may lead to obesity, dyslipidemia, and type 2 diabetes. Because of these connections, the authors believe that CB1 antagonists may hold potential in the treatment of the aforementioned metabolic disorders.

Metabolic Syndrome - Metabolic syndrome in people with a psychotic illness: is cannabis protective?

  • The University of Western Australia
  • 2016

related conditions:

Metabolic Syndrome

This study looks to investigate if the rate of metabolic syndrome in people with psychotic illnesses was associated with the frequency of cannabis use. Researchers found a significant association between metabolic syndrome and frequent use, but not with occasional use. The authors also note cannabis’ potential cardiometabolic protective effect and call for additional research to understand the underlying mechanism at play.

Metabolic Syndrome - Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome

  • Institute of Pharmacology, Charite
  • 2013

related conditions:

Metabolic Syndrome

In this study, researchers examined the effect of CB1 receptor blockade on cardiovascular function after experimental metabolic syndrome. CBD is a known CB1 antagonist. Using rat models, researchers administered the CB1 antagonists over six weeks and measured metabolic responses. Researchers found that CB1 blockade improved heart function, decreased arterial stiffness, and reduced brain natriuretic peptide levels.

CBD Research That Might Be Useful for Symptoms of Metabolic Syndrome

potencial impact research overview

Weight Loss - The endocannabinoid system in obesity and type 2 diabetes

  • National Research Council
  • 2008

related conditions:

Weight Loss

The report concluded the cannabinoid system controls lipid and glucose metabolism in several key ways. Researchers believe metabolic imbalance could be a significant reason excess body fat gets out of control. However, they concluded CBD could help regulate these systems and control weight.

Anxiety - Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

  • University of Melbourne, Australia
  • 2013

related conditions:

Anxiety

A comprehensive review of all the plant-based medicine which has had both preclinical and human clinical trials conducted about their anxiolytic-like effect. An analysis of over 1500 papers identified 21 plants which had been adequately tested, with one of the most successful of these plants found to be CBD enriched Cannabis species.

Inflammation - Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice

  • Tongji University School of Medicine
  • 2013

related conditions:

Inflammation

A study of mice concluded CBD has significant anti-inflammatory effects. The researchers also saw evidence that the expression of the GPR55 receptor was improved after starting on CBD. Treatment with CBD was shown to significantly decrease the levels of several inflammation-related chemicals in test subjects.

Metabolic Syndrome & CBD Research Overview

These days, most people don’t have to go very far to find a ton of different products containing CBD. This is primarily thanks to the pile of new research being published over the last 15 years. While the value of CBD to treat seizures is well documented, researchers are now branching out and asking what else CBD can do. One condition that CBD shows some promise in being able to improve is metabolic syndrome.

A report called The potential use of cannabidiol in the therapy of metabolic syndrome, assessed the ability of CBD to benefit those living with metabolic syndrome. Several of the major benefits of CBD, including its immunomodulating effect, were referenced by the researchers. They believe CBD is potentially invaluable and ought to be researched further in the treatment of metabolic syndrome.

Other studies of CBD and the causes of metabolic syndrome have provided encouraging data. For instance, Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes, provided evidence dysregulation of the endocannabinoid system could result in several risk factors for metabolic syndrome, including obesity, dyslipidemia, and type 2 diabetes.

Some research has shown excessive cannabis use may actually lead to metabolic syndrome. Metabolic syndrome in people with a psychotic illness: is cannabis protective?, concluded that while occasional users didn’t have a higher risk, those who chronically used cannabis were much more likely to face metabolic syndrome. Experts believe CBD could provide benefits while avoiding this obvious pitfall.

The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults studied the impact of cannabinoids, such as CBD, on insulin resistance, glucose production, and fasting insulin, all known to play a significant role in controlling body weight. The researchers analyzed self-reported assessments with blood testing of nearly 5000 subjects and concluded cannabinoid use was associated with a 16% drop in fasting insulin levels, as well as reduced waist size.

Further study into the benefits of CBD for those living with metabolic syndrome has yielded some positive results. Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome, found that restricting the CB1 receptors, which CBD is known to do, can improve overall heart function along with peptide levels and arterial stiffness.

Weight loss is one of the best ways to control metabolic syndrome, but many are challenged by the prospect. However, CBD has been shown to regulate metabolism thanks to reports such as The endocannabinoid system in obesity and type 2 diabetes. The researchers showed the endocannabinoid system impacts lipid and glucose metabolism in important ways. They even believe CBD could one day be part of effective weight management programs.

Anxiety is another relatively common issue that tends to coincide with metabolic syndrome as people may feel increasingly unhappy with their bodies. Luckily, CBD is known to be a potent aid against anxiety, thanks to reports such as Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence. In fact, that review of reports on over1500 plant-based anxiety medications concluded CBD is by far the most powerful.

It’s also worth mentioning that CBD is a powerful tool against inflammation, which is common with metabolic syndrome. Reports like Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice have proven CBD interacts with the GPR55 receptor and improves its functionality. This treatment was observed to reduce inflammation-related chemicals found in the body significantly.

Best CBD for Metabolic Syndrome

NoteCBD Capsules (10mg)

NoteCBD Capsules (10mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$45.00
  • CBD Per Serving: 10mg
  • Number Of Servings: 30
  • Cost Per Serving: $1.50
  • Cost Per/mg of CBD: $0.15
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advantages

  • Full Spectrum
  • Lab Certified
  • Organic
  Servings per day Days supplied in one package Cost per week
Low Dosage (5 mg/day) 0.50 60.0 $5.25
Mid Dosage (20 mg/day) 2.00 15.0 $21.00
High Dosage (50 mg/day) 5.00 6.0 $52.50

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Pure CBD Oil Capsules (15mg)

Pure CBD Oil Capsules (15mg)

description

Every Day Optimal Soft Gel PCR Hemp Oil Capsule contains 15mg pure CBD from our proprietary high CBD strain of hemp.

$59.99
  • CBD Per Serving: 15mg
  • Number Of Servings: 30
  • Cost Per Serving: $2.00
  • Cost Per/mg of CBD: $0.13
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advantages

  • Easy Capsule Form
  • No GMO
  • All Natural
  Servings per day Days supplied in one package Cost per week
Low Dosage (5 mg/day) 0.33 90.0 $4.67
Mid Dosage (20 mg/day) 1.33 22.5 $18.66
High Dosage (50 mg/day) 3.33 9.0 $46.66

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NoteCBD Capsules (25mg)

NoteCBD Capsules (25mg)

description

Enjoy the benefits of hemp extract with the convenience of a capsule. Each capsule contains a pre-portioned dose of full-spectrum hemp extract and MCT oil.

$95.00
  • CBD Per Serving: 25mg
  • Number Of Servings: 30
  • Cost Per Serving: $3.17
  • Cost Per/mg of CBD: $0.13
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advantages

  • Full Spectrum
  • Gluten Free
  • Lab Certified
  Servings per day Days supplied in one package Cost per week
Low Dosage (5 mg/day) 0.20 150.0 $4.43
Mid Dosage (20 mg/day) 0.80 37.5 $17.73
High Dosage (50 mg/day) 2.00 15.0 $44.33

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Suggested CBD Dosage for Metabolic Syndrome

Dosage Per Day

Low

5 mg

Mid

20 mg

High

50 mg

Easily the most common question we get is how much CBD is needed to cure "X" condition. While it would be great to have a simple answer for each person, the truth is a lot more complicated. In order to get the most out of your CBD, you simply must take the time to experiment for yourself.

While we can't give you the exact needed dose, we can offer a solid starting point. According to experts, smaller doses of CBD, around 20mg per day, could be most effective for treating metabolic syndrome. Most researchers agree it's best to start with lower dosages and work your way up as needed.

It's always important to note that while CBD has become a common alternative medication in most places, this isn't the case everywhere. You'll want to avoid finding yourself in hot water by taking CBD somewhere you shouldn't have. Luckily, all it takes is a bit of research before you travel, and you should be okay.

We also take the time to mention that not all CBD products are going to be THC-free. In fact, quite a large selection of CBD-based products will still contain some THC to improve the quality of the product. While this does seem to provide significant benefits, if you're unable or willing to get high, you need to avoid these products.

However you choose to track your progress with CBD, please think about leaving those experiences here for others to learn from. We all remember what it's like to be a newcomer somewhere and feel totally lost. That's why we should work together to ensure everyone has the information they need to succeed.

Tracking CBD Effectiveness For Metabolic Syndrome

One thing that seems to be difficult for people just starting out on CBD to grasp is how to tell if it's actually working for them, and how well. This can be a big hurdle for some, as it makes them feel discouraged, but it 's the case for many conditions, and metabolic syndrome is certainly one of them.

The absolute best thing you can do if you want to maximize the effectiveness of your CBD is to start a journal alongside your new regimen. All you need to do is take down your daily dose, and how you felt that day. After a few weeks, most people feel very well equipped to answer the question of if CBD worked for them.

Everyone is different, and their system may interact with CBD in a slightly different way than others. That's what makes personal experimentation such an essential tool for anyone looking to use CBD to its fullest. You must listen to your body if you want it to be worth your time.

A lot of people ask about whether or not they must keep a journal to ensure they succeed. While plenty of people have found what they were looking for without keeping a journal, those who want to ensure success should try this easy trick.

Anyone who does start tracking their progress with CBD is encouraged to leave those experiences here for the next person to reference. CBD can be a mysterious thing, so the more trustworthy experiences out there, the better. All it takes is a brief description of your time taking CBD, along with a score for how it treated your weight loss, inflammation, and anxiety. Keeping a close eye on your progress is the best way to forge a path forward.

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