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Prostate Cancer overview

Prostate cancer refers to any cancer found in the prostate. The prostate is a small organ, only found in men, that produces the seminal fluid sperm travels in. While some forms of prostate cancer moving extremely slow, others are aggressive and require rapid treatment. When it’s detected early, it can often be treated successfully, but the chances drop once it spreads.

Like many forms of cancer, there is a distinct lack of symptoms in the early stages of prostate cancer. When it becomes more advanced, and symptoms start to appear, they often include trouble urinating, decreased flow, blood in semen, as well as discomfort in pelvis or bones.

Another common complication for those living with prostate cancer is urinary incontinence. This can often be treated relatively easily, however. The treatment will depend on what type of prostate cancer you have, with it ranging from medication to surgery or even a catheter. Some men experience erectile dysfunction when dealing with prostate cancer, with similar treatment options available.

However, one of the most significant complications of any cancer is the metastasizing or spreading to other parts of the body. Prostate cancer is known to spread to nearby organs such as the bladder, but it can also travel through the bloodstream or lymphatic system to reach other parts of the body. Once this occurs, it can still be controlled, but it’s unlikely to be cured, making proper screening vital.

Researchers are still trying to work out precisely what causes prostate cancer. They do know that prostate cancer starts when cells in the prostate become abnormal and cause mutations in the DNA. Over time cells proliferate much faster than they should and damage the healthy tissue. Once these cells grow enough, they can break off and spread to other portions of the body.

The major risk factors for prostate cancer are things you don’t have much control over, such as age, race, and family history. Older men have a greater chance of developing prostate cancer, along with black men and those who have a family history. One risk factor that can be controlled is obesity, with large men who are diagnosed being much more likely to have an advanced case.

Aside from skin cancer, prostate cancer is the most common type of cancer in men, with nearly 175,000 men in the US set to be diagnosed this year alone. Older men are by far at the highest risk, with about 60% of cases occurring at ages 65-plus.

Cancer of any kind is a severe diagnosis and should be treated as such. Be sure to talk to your doctor as soon as possible if you’re worried you or a loved one may be dealing with prostate cancer. Only a professional can offer a real diagnosis and the most logical path forward.

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Table of Contents

CBD Research For Prostate Cancer

potencial impact research overview

Prostate Cancer - Towards the use of non-psychoactive cannabinoids for prostate cancer

  • National Institutes of Health
  • 2013

related conditions:

Prostate Cancer

Researchers analyzed the palliative effects of cannabis and related cannabinoids in helping to provide relief to cancer patients. The authors note the potentially-adverse psychoactive effects of THC and the benefit that further research into non-psychoactive cannabinoids such as CBD may provide. They conclude that these cannabinoids may offer a novel therapeutic agent in the treatment of various complications of cancer.

Prostate Cancer - In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines

  • University of British Columbia
  • 2014

related conditions:

Prostate Cancer

In this study, researchers looked into the role non-psychoactive cannabinoids such as CBD may play in helping to treat and manage symptoms of prostate cancer and related therapies. Their research found that CBD is a potent inhibitor of cancer cell growth, and notably is significantly less potent in non-cancer cells. Their research concludes that CBD and other non-psychoactive cannabinoids may help treat other forms of cancer as well.

Prostate Cancer - Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent

  • Texas A&M University
  • 2011

related conditions:

Prostate Cancer

The researchers wanted to test the hypothesis that the anticancer activity of cannabinoids is linked to the induction of phosphatases. The team found that CBD inhibited cell growth and induced apoptosis. While cannabinoid receptor agonists induce phosphatases and apoptosis in cancer cells, this effect was ligand-dependent and must be studied further.

Prostate Cancer - Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer

  • University of Naples Federico II
  • 2012

related conditions:

Prostate Cancer

This study investigates the potential chemopreventive effects of CBD on colon cancer in mice models. They believe CBD’s antioxidant, anti-inflammatory effects, along with the ability to prevent enzymatic degradation, are all key to helping cancer patients. Researchers found that CBD helped protect DNA from oxidative damage, increased endocannabinoid levels, and reduced cell proliferation.

Prostate Cancer - Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol

  • University of Naples Federico II
  • 2014

related conditions:

Prostate Cancer

The team of researchers investigated the impact of CBD on colorectal cancer cell proliferation. They found that CBD reduced cell proliferation in tumoral but not healthy cells. This highlights the suggested "selective nature" of CBD. Researchers conclude their results may be beneficial in researching cannabis-based drugs for the treatment of cancer.

CBD Research That Might Be Useful for Symptoms of Prostate Cancer

potencial impact research overview

Anxiety - Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

  • University of Melbourne, Australia
  • 2013

related conditions:

Anxiety

A comprehensive review of all the plant-based medicine which has had both preclinical and human clinical trials conducted about their anxiolytic-like effect. An analysis of over 1500 papers identified 21 plants which had been adequately tested, with one of the most successful of these plants found to be CBD enriched Cannabis species.

Inflammation - Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice

  • Tongji University School of Medicine
  • 2013

related conditions:

Inflammation

A study of mice concluded CBD has significant anti-inflammatory effects. The researchers also saw evidence that the expression of the GPR55 receptor was improved after starting on CBD. Treatment with CBD was shown to significantly decrease the levels of several inflammation-related chemicals in test subjects.

Nausea - Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews

  • Palo Alto University, CA, USA
  • 2017

related conditions:

Nausea

CBD was shown to significantly suppress vomiting in lab rats and shrews. Researchers used another substance, known as cannabigerol (CBG) to reverse this suppression. Moderate doses of CBG and CBD are opposing each other at the 5-HT1A receptor, which is known to play an essential role in regulating nausea.

Prostate Cancer & CBD Research Overview

In just a few short years, CBD has seemingly gone from a little thought about alternative medication to the hottest thing in natural medicines. This is due, in large part, to the growing body of peer-reviewed evidence, which has shed light on the many benefits of CBD, including for men with prostate cancer.

While this is still a relatively new discovery, reports such as In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines still provide incredible results. The team concluded that CBD is a potent inhibitor of prostate cancer cell growth. Even more importantly, they determined CBD doesn’t inhibit the growth of healthy cells.

Other studies have focused on the power of CBD to improve quality of life during palliative care. Towards the use of non-psychoactive cannabinoids for prostate cancer noted how THC provides many benefits but has psychoactive effects, which can be an issue. The team concluded that CBD offers novel therapeutic benefits in the treatment of many prostate cancer complications during palliative care.

Some reports have even shown many benefits of CBD are valuable in the treatment of various types of cancer. For instance, Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent found that the anticancer properties of CBD are linked to phosphatases. Ultimately, they concluded CBD mitigated cancer cell growth in both prostate and colon cancers. Despite identifying cannabinoid receptor agonists, such as CBD, induce phosphatases and apoptosis, researchers believe this effect needs to be studied further.

Further studies into this connection have also revealed some interesting results. Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer highlighted how CBD’s ability to prevent enzymatic degradation, along with the general anti-inflammatory benefits, could be a major key to controlling cancer proliferation.

Other reports have backed up this finding, with Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol finding CBD reduced cell proliferation in tumoral, but not healthy cells. The team believes their research suggests CBD should be studied further as part of a treatment for a wide range of cancers.

CBD has also been proven to benefit those living with prostate cancer in a number of peripheral ways. Most people who are diagnosed with cancer will face a certain amount of anxiety, and this can often become difficult to handle. That said, CBD is known to be one of the most powerful plant-based anxiety medications we have. Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence analyzed over 1500 papers before naming CBD the single best natural treatment for anxiety.

Another common side effect of many types of cancer that CBD has been shown to improve is painful inflammation. Many reports, including Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice, have shown the powerful anti-inflammatory benefits of CBD. They concluded that this effect was due, in part, to an interaction with the GPR55 receptor.

Some types of cancers, and many types of cancer treatments, are known to cause severe nausea. This can be regulated thanks to CBD, however. According to reports such as Interaction between non-psychotropic cannabinoids in marijuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews, CBD owes its powerful anti-nausea effect due to an interaction with the 5-HT1A receptors.

Best CBD for Prostate Cancer

Everyday Optimal CBD Capsules (200mg)

Everyday Optimal CBD Capsules (200mg)

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  • Cost Per/mg of CBD: $0.05
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Mid Dosage (125 mg/day) 0.63 48.0 $43.75
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Pure CBD Oil Capsules, (50mg)

Pure CBD Oil Capsules, (50mg)

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  • CBD Per Serving: 50mg
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  • Cost Per/mg of CBD: $0.08
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Everyday Optimal CBD Oil Tincture (4000mg)

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  • CBD Per Serving: 133.33mg
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  Servings per day Days supplied in one package Cost per week
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Mid Dosage (125 mg/day) 0.94 32.0 $63.44
High Dosage (230 mg/day) 1.73 17.4 $116.72

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Suggested CBD Dosage for Prostate Cancer

Dosage Per Day

Low

30 mg

Mid

125 mg

High

230 mg

It seems like every day, we're asked what the precise dose needed to treat a given condition or symptom is. We sincerely wish that we could just supply everyone who's looking for this answer with a simple number. Sadly, the only way to determine your ideal routine is to try different things out.

Despite not having a precise answer to these questions, we can get you off on the right foot. Experts believe that CBD has the ability to control tumor growth and spread, with THC potentially bolstering these effects a bit. The team showed CBD was well tolerated in high doses, even exceeding 700mg per day. They suggest starting around 20-40mg and working up while paying attention to your body and symptoms.

Many people tend to forget, but CBD still isn't legal everywhere. After many years of facing a complicated legal status, CBD is now legal in most places, but not all. Some places still treat CBD and THC as basically the same, making it illegal to have or use. That said, this won't be a problem for you unless you forget to double-check the law before taking CBD with you somewhere you shouldn't.

It's also important to mention that while most CBD products tend to be CBD only, many still have a bit of THC. This is primarily because some find this helps bolster the desired effects, with research backing its impact on any anti-tumoral effects. However, if you're unwilling or unable to get high, you must make sure you only get THC-free products from here on out.

We sincerely hope you choose to leave your experiences here for the next person to learn from. There's so much evidence out there, it can be really great to get some simple user-generated information to balance all the hard data. Our main goal is to create an excellent platform for connecting CBD users via their experiences. Will you join us in this fight to connect as many people as we possibly can?

Tracking CBD Effectiveness For Prostate Cancer

It’s very common for people who have just started taking CBD to have trouble deciding if it’s actually working for them or not. While this can be discouraging, don’t feel like you’re doing anything wrong, or you’re alone. Even when working properly, CBD has a relatively subtle impact that can be tough to nail down at first.

The best tool we can suggest to those looking to answer this common problem is actually just a simple journal. While it may not seem like a lot, we promise that by tracking your daily doses along with the subsequent symptoms, you’ll be able to determine for sure whether or not CBD has been successful for you. What’s better, most people find it only takes a week or two.

Each person has a different system that may require different regimens to get the most out of the cannabidiol. What’s the perfect mixture for one person could be not nearly enough for another. That’s why we always tell users to pay attention to their bodies first and foremost.

A very common question we’re asked is if the journals are indispensable. While it’s true that not keeping a journal may still result in success, it’s a good idea if you want to do everything you can to maximize your CBD. This is an easy and cheap way to zero in on your ideal plan.

Whichever way you choose to track your progress with CBD, please consider leaving your experiences here for others to learn from. We all hold a small piece to the puzzle, and by working together, we can provide actionable knowledge to those who need it most. Simply leave a brief description of your time using CBD, along with a score for how well it improved any inflammation, anxiety, or nausea issues.

Written By
John Mace Alois is lead content creator at the Did CBD Work? project. He’s analyzed over 400 research papers related to Cannabidiol and helped publish over 55 works related to different conditions for the project. He majored in Cultural Anthropology, with a minor in English, from the University at Albany. He is an avid collector of art supplies and refurbishes old furniture in his spare time.

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